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This review discusses the roles of various PLA2 enzymes in skin health and disease, highlighting potential pathways for future diagnosis and therapy, but it reports no new clinical results.

This study found that wool felting in Ukrainian Carpathian Mountain sheep is linked to significant changes in fatty acid composition, particularly highlighting a decrease in 18-methyleicosanoic acid in bound lipids, suggesting it as a potential marker for cuticle lipid layer damage during felting.

This study reports the development of a fluorescent ionic liquid that shows high sensitivity and selectivity for detecting dextran sulfate sodium, with potential applications in clinical diagnostics and environmental monitoring.

This study found that scanning electron microscopy with argon sputter etching visualizes hair lipids at the cell membrane complex as distinctive convex structures, shedding light on their role and localization in human hair.

This study observed that eco-friendly PALF forms a protective physical barrier on the skin, helping limit the impact of environmental pollutants and offering additional benefits for skin and hair in various cosmetic formulations.

This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.

This case report highlights a female patient with familial partial lipodystrophy who showed significant improvement in liver stiffness after starting leptin replacement therapy.

This study found that lipin 1β expression in both visceral and subcutaneous adipose tissue is significantly lower in PCOS patients compared to controls, suggesting its involvement in the pathogenesis of insulin resistance.

This study found that PLDζ2 and NPC4 enzymes play distinct roles in lipid remodeling and root hair growth in Arabidopsis under phosphate deficiency, influencing root hair density and length in a tissue- and time-specific manner.

This study found that a conditioner treatment using 18-MEA combined with a specific cationic surfactant effectively restored hydrophobicity and reduced friction on damaged hair surfaces.

This study found that peptidylarginine deiminase type III and trichohyalin are coincidentally expressed in the infant rat hair follicle, but trichohyalin deimination occurs after their expression during development.

In this study, researchers observed that knocking down the LPA 4 receptor in zebrafish embryos led to vascular and lymph vessel development abnormalities, including edema and decreased heartbeats.

This study reports that a newly developed polyherbal phospholipid complex cream containing Citrus auranticum and Glycyrrhiza glabra extracts improved polyphenol retention in the skin, suggesting potential as an anti-aging cosmeceutical.

This study developed an effective and reliable HPTLC method for the simultaneous measurement of linoleic acid and oleanolic acid in Eclipta alba.

This study found that the DPP-4 inhibitor linagliptin slowed the progression of premature aging characteristics in klotho-/- mice, including improved body weight, cognitive function, and hair retention.

This study reviews the emerging role of protein S-palmitoylation in dermatology, highlighting its impact on skin functions like inflammation and barrier maintenance, and evaluating its potential as a therapeutic target for skin disorders such as alopecia and psoriasis.

This study found that while systemic absorption of DHT from liposomes was negligible, the topical biological effect was weaker compared to DHT dissolved in acetone on the female hamster flank organ model.

This study identified key lipid differences between black and white hair in individuals with premature greying, highlighting vitamin D3 as a potential target for further research in understanding this condition.

This review discusses the regulatory roles of lysophospholipids like LPA and S1P in diseases such as fibrosis, neuropathic pain, and cancer, but reports no new clinical results.

This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.

This study found that DHHC13 is crucial for hair anchoring and skin barrier function, with its deficiency in Zdhhc13(skc4) mice leading to cyclic alopecia and skin abnormalities due to cornifelin deficiencies.

This study found that soaking raw skin in a saturated lime solution led to widespread cellular dissolution and tissue changes that facilitate dehairing after 4 to 7 days at -18°C.

This study suggests that trichohyalin is modified by peptidyl-arginine deiminase before being cross-linked by TGase 3, allowing the formation of rigid structures in hair follicle cells.

This review discusses temporary chemical hair removal methods involving thioglycolates and other compounds but reports no new clinical findings; the authors highlight interest in natural-based substances.

This study found that biodegradable PLA particles released fluorochromes in a time-dependent manner on human skin, with BP-PLA particles releasing rapidly and DiAsp-PLA particles providing sustained release and accumulation in hair follicles.

This study observed that PAD type III and trichohyalin are expressed earlier than their deiminated form during the first and second hair cycles in rat hair follicles, indicating a potential additional factor is involved in triggering deimination.

This study reported that an injectable hydrogel based on platelet-rich plasma and laponite improved wound healing in diabetic and normal rats by enhancing angiogenesis and macrophage polarization.

This study identified three Ayurvedic compounds that may serve as potential treatments against the macrolide-resistant enzyme murE of *Tropheryma whipplei*, addressing challenges in treating Whipple disease.

New method effectively analyzes finasteride and its stability.

This study demonstrated that the IVL-DrugFluidic® platform is effective for mass-producing finasteride-loaded polymeric microspheres for long-acting injectables, maintaining stable drug release without an initial burst for a month.