ToF-SIMS Characterization of the Lipid Layer on the Hair Surface: Effect of the 18-MEA Lipid Layer on Surface Hydrophobicity

    Masayuki Okamoto, Noriyuki Tanji, Taichi Habe, Shigeto Inoue, Shinichi Tokunaga, Hiroto Tanamachi
    TLDR 18-MEA is essential for hair's water resistance, and a conditioner with 18-MEA and SPDA can restore it.
    This study examined the impact of 18-MEA damage on hair surface hydrophobicity and the effectiveness of replenishing this lipid layer using ToF-SIMS. It was found that 18-MEA levels significantly decreased in Japanese women who underwent coloring treatments, especially those treated more than twice a year. Even untreated hair showed over 80% loss of 18-MEA at 40 cm from the root. The study demonstrated that 18-MEA is crucial for maintaining surface hydrophobicity. A conditioner treatment combining 18-MEA with Stearoxypropyldimethylamine (SPDA) was effective in restoring and maintaining hydrophobicity and reducing friction on damaged hair surfaces.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Regrowth 21 months, fin, 41 Male

      in Progress Pictures  592 upvotes 1 year ago
      A user shared their 21-month hair regrowth journey using oral Finasteride 1mg daily and Minoxidil 5% topical applications. Despite initial discouragement due to slow progress, they saw significant improvement, reducing the need for a hair transplant to minor fill-ins at the front hairline.

      community My microneedling journey (no min, fin, etc)

      in Microneedling  210 upvotes 3 months ago
      The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

      community M26 - 9 months after hair transplant! AMA

      in Transplants  624 upvotes 5 years ago
      A user who underwent a hair transplant in Istanbul to reduce balding, and the discussion of various treatments such as finasteride and growth hormone for preventing further hair loss.
      [object Object]

      community Comprehensive Microneedling Guide

      in Microneedling  293 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community What was your “f*ck I’m balding” story?

      in Chat  178 upvotes 1 year ago
      User noticed thinning hair at 18-19, started finasteride at 22 and minoxidil at 24, with positive results. Others shared hair loss experiences and treatments, including finasteride, minoxidil, and hair transplants.

    Similar Research

    5 / 1000+ results