research Review of Hair Follicle Dermal Cells
Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
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540-570 / 1000+ results research Human Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth
Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
research Scarless Wound Healing: Transitioning from Fetal Research to Regenerative Healing
Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
research Histologic Changes in the Skin of Hairless Mice Following Peeling With Salicylic Acid
The study examined the effects of salicylic acid peeling on hairless mice skin, using concentrations of 7.5%, 15.0%, and 30.0%. The 30.0% concentration led to significant exfoliation, epidermal thinning, and increased basal cell proliferation within 24 hours, without causing degeneration or inflammation. Lower concentrations caused minimal changes. The findings indicated that salicylic acid could safely regenerate the epidermis and papillary dermis by injuring the cornified layer without inflammation, suggesting its potential as a chemical peeling method for individuals at risk of pigmentary disorders and keloids. The macrogol vehicle was less irritating than ethanol, which could be advantageous for sensitive patients.
research Going Below and Beyond the Surface: Microneedle Structure, Materials, Drugs, Fabrication, and Applications for Wound Healing and Tissue Regeneration
Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
research Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration After Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus
Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
research Animal and In Vitro Models for the Study of Hair Follicles
The document reviewed various in vitro and in vivo models used to study hair follicles, focusing on their role in understanding hair growth and disorders like androgenetic alopecia and alopecia areata. It discussed the use of genetically modified animals and cell cultures, such as dermal papilla cells, to explore the biological and biochemical mechanisms of hair follicles. These models provided insights into the effects of androgens and growth factors on hair growth, highlighting the importance of synthesizing information from different models due to the unique characteristics of human hair growth. The research aimed to facilitate a better understanding of hair follicle function and aid in developing novel treatments for hair disorders.
research Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors
Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
research Inhibition of Wnt/β-Catenin Pathway Promotes Regenerative Repair of Cutaneous and Cartilage Injury
Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.
research Cellular and Extracellular Involvement in the Regeneration of the Rat Lower Vibrissa Follicle
Both cell and non-cell parts are important for rat whisker follicle regrowth.
research As a Carrier–Transporter for Hair Follicle Reconstitution, Platelet-Rich Plasma Promotes Proliferation and Induction of Mouse Dermal Papilla Cells
Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
research Rescuing Key Native Traits in Cultured Dermal Papilla Cells for Human Hair Regeneration
Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
research Overview of Urethral Reconstruction by Tissue Engineering: Current Strategies, Clinical Status, and Future Direction
The best method for urethral reconstruction is using hypoxia-preconditioned stem cells with autologous cells on a vascularized synthetic scaffold.
research After Skin Wounding, Noncoding dsRNA Coordinates Prostaglandins and Wnts to Promote Regeneration
After skin is damaged, noncoding dsRNA helps prostaglandins and Wnts work together to repair tissue and promote hair growth.
research Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis
Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Fabrication and Biological Evaluation In Vivo of an Injectable Keratin Hydrogel as Filler Materials
Keratin hydrogel from human hair is a promising biocompatible material for soft tissue fillers.
research Platelet-Rich Plasma as a Site-Targeted Approach in Wound Healing: A Molecular Perspective
Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.
research Self-Assembled Complete Hair Follicle Organoids by Coculture of Neonatal Mouse Epidermal Cells and Dermal Cells in Matrigel
Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
research The Effect of Ovine Secreted Soluble Factors on Human Dermal Papilla Cell Aggregation
Sheep-derived factors improve human hair cell clustering, which may help hair growth.
research Dynamic Evaluation of Pathological Changes in a Mouse Acne Model by Optical Imaging Technology
New imaging techniques can assess and track changes in mouse acne without harm, aiding treatment choices.
research Human Adipose Tissue-Derived Small Extracellular Vesicles Promote Soft Tissue Repair Through Modulating M1-To-M2 Polarization Of Macrophages
Tiny fat-derived particles can help repair soft tissues by changing immune cell types.
research Adipose-Derived Stem Cells in Skin Diseases, Wound Healing, and Skin Defects: A Review
Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
research Production and Characterization of Human Hair Keratin Bioplastic Films With Novel Plasticizers
Human hair was used to make biodegradable plastic films that could be useful for packaging and disposable products.
research An Advanced Review: Polyurethane-Related Dressings for Skin Wound Repair
Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.
research Exploring Rat Corpus Cavernosum Alterations Induced by Finasteride Treatment and Withdrawal
Finasteride changes hormone levels and certain proteins in rats, but these effects can be reversed after stopping the drug.
research Efficient Scarless Skin Regeneration Enabled by Loading Micronized Amnion in a Bioinspired Adhesive Wound Dressing
A new hydrogel with micronized amnion helps achieve better, scar-free skin healing.
research Harnessing Mesenchymal Aggregation for Engineered Organ-Level Regeneration: Recent Progress and Perspective
Scientists are using clumps of special stem cells to improve organ repair.
research IPSC-Based Approach for Human Hair Follicle Regeneration
The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
research Degeneration in Dermatopathology
The document concludes that understanding tissue degeneration is crucial for diagnosing skin lesions.