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This review explores the potential of nanofiber scaffolds as an advanced intervention in peripheral nerve regeneration, detailing their fabrication, cellular interactions, controlled bioactive agent release, clinical translation prospects, emerging trends, and biocompatibility considerations for treating peripheral nerve injuries.

This study investigated nanocomposite scaffolds made from alginate, chitosan, and graphene oxide to promote the proliferation of spermatogonial stem cells, finding the ALGCS/GO30 scaffold to be particularly effective due to increased proliferation markers and PLZF protein expression compared to controls.

This review discusses the role of extracellular vesicles in bone regeneration and their potential as therapeutics, highlighting challenges like standardization and safety for clinical application, but it reports no new clinical results.

This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.

This review highlights that synthetic biodegradable polymers like PVA, PCL, PLA, PLGA, PU, and PEO/PEG can address the limitations of natural polymers in wound healing, offering improved mechanical properties and slower degradation, thereby enhancing their application as wound dressings.

Wharton's Jelly stem cell medium may help treat skin issues in Systemic Sclerosis.

This study systematically reviews the development and applications of drug-loaded nanofiber scaffolds in wound healing, highlighting challenges such as maintaining drug activity and achieving controlled release, while summarizing preparation methods and describing advanced drug delivery schemes.

This study developed immortalized human hair follicle-derived mesenchymal-like stromal cells (iHF-MSCs) as a consistent source of therapeutic secretome, reporting their superior immunomodulatory and regenerative performance, potentially advancing cell-free therapies for inflammation and tissue repair.

This study explores the transformative role of tissue engineering in cosmetics, highlighting innovations like lab-grown skin and personalized grafts that enhance product efficacy, offer ethical alternatives to animal testing, and address aesthetic issues such as scarring and aging.

This review examined mechanisms regulating muscle repair, highlighting disruptions in aging and chronic diseases like Duchenne muscular dystrophy and diabetes. It noted that chronic inflammation and metabolic dysfunction hinder effective regeneration and discussed emerging therapies, suggesting multi-target approaches could be promising despite limited clinical evidence.

In this review, it is discussed how mesenchymal stem cell aggregation plays a crucial role in organ development and has potential applications in organ regeneration through tissue engineering.

In this study, porcine collagen acellular dermal matrix scaffolds combined with mice platelet-rich plasma were associated with increased hair density and follicle regeneration in mice with alopecia, suggesting a potential therapeutic approach.

In this study, immobilized VEGF selectively captured endothelial cells under various shear stresses, suggesting its potential for promoting endothelialization in vascular grafts or implanted tissues.

This study introduces a novel in vitro model for clubfoot fibrosis to enable high-throughput drug screening and found that while the model increased collagen deposition, the antifibrotic drug minoxidil effectively inhibited the expression of collagen cross-linking enzymes.

This review found significant progress in 3D bioprinting for surgery, noting advances in creating complex tissue constructs, while highlighting ongoing challenges like vascularization and integration with host tissue, emphasizing the need for further research and regulatory development.

In this study, researchers reviewed the progress and challenges in using hydrogels for 3D printing in biomedical applications, highlighting advancements in structural complexity, and identifying ongoing issues like resolution improvement, cell viability, and ethical concerns for clinical use.

This review highlights the rapid advancements in 3D bioprinting techniques, emphasizing their role in enhancing regenerative therapy, drug delivery, and bioengineering applications while addressing current challenges in bioink formulation and bioprinting stability.

This perspective highlights how advancements in single-cell sequencing and digital pathology can help understand the complex mechanisms of immune responses, fibrosis, and tissue remodeling related to medical implants, aiming to address the challenges of implant-related tissue reactions reported in this study.

This review examines the potential of mesenchymal stem/stromal cells in treating and possibly preventing allergic diseases, and reports no new clinical results.

This review highlights advancements in 3D bioprinting for skin tissue engineering, focusing on exosome-loaded bioinks that show potential for enhancing skin regeneration and repair.

This review discusses the evolution of adipose tissue research in regenerative medicine, from tissue transfer to cell-free bioengineering applications, highlighting its therapeutic potential, current limitations, and future directions.

This article discusses how designing biomaterials to modulate immune responses has become a promising strategy for enhancing tissue repair and regeneration.

This review highlights that skin organoids, advanced three-dimensional models mimicking human skin, are emerging as effective alternatives to traditional culture models and human skin, overcoming limitations of two-dimensional systems and ethical concerns, and are being increasingly used in areas like developmental biology and disease modeling.

This review discusses various tissue engineering approaches for hair follicle regeneration and biomaterials used, emphasizing its potential despite current clinical challenges.

This study found that exosomes from different mesenchymal stem cell sources had distinct effects on immune cell functions and varied microRNA expression profiles compared to their original cells.

This study found that dendritic epidermal T cells and their exosomes enhance epidermal stem cell proliferation, accelerating wound re-epithelialization in the skin.

This study found that Muse cells, when injected subcutaneously, alleviated symptoms of atopic dermatitis in mice, suggesting potential for treating inflammatory skin conditions.

This review discusses regenerative medicine approaches for treating alopecia, including mesenchymal stem cell therapies and platelet-rich plasma, but reports no new clinical results, emphasizing the need for further study.

In this study, MSC-derived magnetic nanovesicles combined with a magnetic field increased skin retention and accelerated hair follicle growth in a mouse model of hair regeneration.

This review explores the cellular mechanisms of tissue repair and discusses how advancements in understanding wound pathology could lead to the development of more effective therapies for chronic, non-healing wounds, which are prevalent among individuals with diabetes and aging.