How Advancing Is Peripheral Nerve Regeneration Using Nanofiber Scaffolds? A Comprehensive Review of the Literature

Nanofiber scaffolds are highlighted as a promising intervention for enhancing peripheral nerve regeneration, addressing the challenges posed by the body's limited natural healing processes. This comprehensive review delves into the fabrication methods of nanofibers, their interactions with cellular entities, strategies for controlled release of bioactive agents, and the prospects for clinical translation. It also explores emerging trends and considers biocompatibility and safety. By elucidating the structural and functional capacities of nanofiber scaffolds, the review aims to present an effective strategy for treating peripheral nerve injuries.