Spatial and Single-Cell Transcriptomics Unravel the Complex Interplay Between the Body and Medical Implants

    May 2025 in “ Cell Biomaterials ”
    Nona Farbehi, Hamid Alinejad-Rokny, Tatyana Chtanova, Jelena Rnjak‐Kovacina
    Studysummary This perspective highlights how advancements in single-cell sequencing and digital pathology can help understand the complex mechanisms of immune responses, fibrosis, and tissue remodeling related to medical implants, aiming to address the challenges of implant-related tissue reactions reported in this study.
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    Research cited in this study 1

    1. Tracing Immune Cells Around Biomaterials With Spatial Anchors During Large-Scale Wound Regeneration Nature Communications · 2023