Temporal Dynamics of Endothelium After Radiation Injury Reveal a Transient Pro-Angiogenic Capillary Subpopulation Associated With Skin Repair

    March 2026 in “ International Journal of Molecular Sciences ”
    Xuejiao Ren, Y. Cai, Chengming Gao … Pengbo Cao
    Studysummary In this laboratory study, researchers observed that mouse vascular endothelial cells exhibit dynamic changes after exposure to ionizing radiation, including a transient endothelial subpopulation that facilitates vascular-epidermal communication and skin repair, with shifting roles in angiogenesis and immune surveillance over time.
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    Research cited in this study 4

    1. Radiation Dermatitis: Radiation-Induced Effects on the Structural and Immunological Barrier Function of the Epidermis International journal of molecular sciences · 2024
    2. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
    3. The Immune Functions of Keratinocytes in Skin Wound Healing International Journal of Molecular Sciences · 2020
    4. Recent Advances in the Epidermal Growth Factor Receptor/Ligand System Biology on Skin Homeostasis and Keratinocyte Stem Cell Regulation Journal of Dermatological Science · 2013