April 2026 in “Frontiers in Cell and Developmental Biology” This study found that PGRP-S expression in mouse epidermis is specific to certain hair follicle epithelia, depending on the skin region, and can be transiently induced in flank skin hair follicle epithelium after exposure to Staphylococcus aureus, suggesting a role in environmental surveillance.
September 2025 in “Cell Reports” This study found that a single instance of acute skin stretching can enhance immune surveillance and improve vaccine delivery by increasing skin permeability and promoting immune cell recruitment without causing tissue damage.
June 2026 in “Journal of Investigative Dermatology” Aging weakens sweat glands due to reduced support from immune cells, but treatments may help restore function.
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February 2018 in “Immunity” In this study, researchers found that quiescent stem cells resist immune attack due to downregulated antigen presentation, which may help explain the immune evasion of early cancer-initiating cells.
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August 2024 in “Journal of Translational Medicine” This review explores recent advancements in understanding how various physiological and psychological factors, such as stress and aging, influence epidermal stem cell populations, highlighting their importance in immune-related skin disorders and potential for clinical applications.