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    Glossary CXCL10

    signaling protein that attracts immune cells to inflammation sites

    CXCL10, also known as Interferon gamma-induced protein 10 (IP-10), is a type of signaling protein called a chemokine. It plays a crucial role in the immune system by attracting white blood cells to sites of inflammation or infection. This protein is particularly important in conditions where the immune response needs to be regulated, such as autoimmune diseases and certain types of hair loss like alopecia areata.

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    Research 30 of 872

    1. Increased Circulating CXCL10 in Non-Segmental Vitiligo Concomitant with Autoimmune Thyroid Disease and Alopecia Areata Annals of Dermatology · 2019 · 17 citations
    2. Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing Frontiers in Immunology · 2024 · 7 citations
    3. Th1 Chemokine CXCL10 and Alopecia Areata: The Possible Target for the Treatment of Alopecia Areata Journal of Clinical & Cellular Immunology · 2016 · 3 citations
    4. CXCL12 Neutralizing Antibody Promotes Hair Growth in Androgenic Alopecia and Alopecia Areata International Journal of Molecular Sciences · 2024
    5. CXCL12 inhibits hair growth through CXCR4 Biomedicine & Pharmacotherapy · 2022
    6. The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles Differentiation · 2009 · 57 citations
    7. CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17 The Journal of Experimental Medicine · 2024 · 32 citations
    8. Polymorphisms in the promoter regions of the CXCL1 and CXCL2 genes contribute to increased risk of alopecia areata in the Korean population Genetics and Molecular Research · 2015 · 8 citations
    9. Combination of an engineered <i>Lactococcus lactis</i> expressing CXCL12 with light‐emitting diode yellow light as a treatment for scalded skin in mice Microbial biotechnology · 2021 · 6 citations
    10. Insights into the context-dependent immunological roles of the CXCL12–CXCR4 axis in alopecia Frontiers in Immunology · 2026
    11. Hypoxia-Derived Mesenchymal Stem Cell Exosomes Downregulate CXCL12 and Upregulate IL-10 Expression in a Murine Model of Androgenic Alopecia Molecular and Cellular Biomedical Sciences · 2026
    12. Regulatory T cells in skin utilize the Cxcr4-Cxcl12 axis to promote hair follicle regeneration Cell Reports · 2025
    13. CXCL12 Drives Reversible Fibroimmune Remodeling in Androgenetic Alopecia Revealed by Single-Cell RNA Sequencing International Journal of Molecular Sciences · 2025
    14. EVALUATION OF THE ROLE OF CXCL12 IN CASES OF ALOPECIA AREATA ALEXMED ePosters · 2025
    15. Differential Expression of CXCL12 in Human and Mouse Hair: Androgens Induce CXCL12 in Human Dermal Papilla and Dermal Sheath Cup International Journal of Molecular Sciences · 2024
    16. Correlation Analysis of CXCL10, FOS, HOXC13, and WNT4 Gene Polymorphisms with Key Economic Traits—Initial Population Screening for Jiangnan Cashmere Goats Genes · 2025
    17. Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA) Journal of the American Academy of Dermatology · 2015 · 157 citations
    18. Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers Experimental Dermatology · 2016 · 70 citations
    19. CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata Journal of Immunology · 2016 · 64 citations
    20. Morphea: progress to date and the road ahead Annals of Translational Medicine · 2021 · 50 citations
    21. Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development 2012 · 48 citations
    22. Reconstructed human skin shows epidermal invagination towards integrated neopapillae indicating early hair follicle formation in vitro Journal of Tissue Engineering and Regenerative Medicine · 2020 · 29 citations
    23. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020 · 20 citations
    24. Antroquinonol Exerts Immunosuppressive Effect on CD8<sup>+</sup> T Cell Proliferation and Activation to Resist Depigmentation Induced by H<sub>2</sub>O<sub>2</sub> Oxidative medicine and cellular longevity · 2017 · 11 citations
    25. The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches JCI Insight · 2023 · 6 citations
    26. Candidate Gene Analysis Of Alopecia Areata In Jordanian Population Of Arab Descent: A Case–Control Study The application of clinical genetics · 2019 · 6 citations
    27. Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging Frontiers in Cell and Developmental Biology · 2021 · 5 citations
    28. Future Directions in the Treatment of Vitiligo 2018 · 3 citations
    29. PRF Lysates Modulate Chemokine Expression in Oral Squamous Carcinoma and Healthy Epithelial Cells Bioengineering · 2024 · 2 citations
    30. 1322 Molecular profiling of frontal fibrosing alopecia (FFA) reveals TH1 and JAK-STAT up-regulation with no suppression of hair keratins Journal of Investigative Dermatology · 2018 · 2 citations