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New Australian advertising rules improved stem cell marketing practices but further regulation is needed for consumer safety.

Higher levels of certain DNAs in blood may indicate hair follicle damage in alopecia areata patients.

Patients in Australia underwent costly, unproven stem cell treatments due to weak regulations and aggressive marketing.

Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.

Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.

Blocking CCR5 can prevent and improve hair loss in alopecia areata.

Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.

Human hair follicles have a unique way of using energy and might use the Cori cycle; blocking CCR5 could help treat hair loss.

Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.

Prasugrel is better than clopidogrel at preventing heart damage and improving blood flow in small heart vessels during heart artery procedures.

Estrogen increases a growth factor in hair cells which might affect hair loss.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Aging causes skin stem cells to work less effectively.