3 citations,
February 2023 in “Journal of drug delivery science and technology” The new drug carriers show promise for better targeting and treating ovarian cancer.
42 citations,
December 2016 in “Cell Death & Differentiation” Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
23 citations,
December 2013 in “Regenerative Medicine” Hair follicle culture helps develop new treatments for hair loss.
81 citations,
February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
41 citations,
January 2007 in “Journal of Korean Medical Science” Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.
28 citations,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
16 citations,
May 2015 in “Tissue Engineering Part C-methods” A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.
15 citations,
April 2001 in “Journal of Dermatological Science” KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.
13 citations,
January 2017 in “Chemical & Pharmaceutical Bulletin” Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.
8 citations,
September 2013 in “Molecular carcinogenesis” Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
4 citations,
February 2022 in “Experimental Dermatology” Hair loss in men might be linked to changes in cell energy factories.
2 citations,
April 2021 in “Journal of Cosmetic Dermatology” Brassica oleracea extract, glucosinlates, and sulforaphane can boost hair growth and might be used to treat hair loss.
1 citations,
February 2016 in “Cell Transplantation” Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
January 2024 in “Journal of tissue engineering” Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
January 2006 in “Seibutsu Butsuri” Curly and straight hair differ in how their internal fibers are arranged.
March 2018 in “John Wiley & Sons, Ltd eBooks” Surgical therapies for vitiligo vary in effectiveness, with combination therapy and medical tattooing recommended for better results.
349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
228 citations,
September 2012 in “Trends in Neurosciences” Nerves are crucial for the regeneration of various body parts in many animals.
222 citations,
January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
156 citations,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
118 citations,
August 2010 in “Developmental Cell” MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
85 citations,
July 2002 in “Pigment Cell Research” The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
78 citations,
October 2012 in “Biomaterials” Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
75 citations,
May 1986 in “Clinics in endocrinology and metabolism” Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
60 citations,
April 2006 in “International Journal of Dermatology” Surgical methods like suction blister grafting and split-thickness skin grafting are highly successful for vitiligo repigmentation, but choosing the right patients is crucial for success.
58 citations,
November 2013 in “Journal of Innovative Optical Health Sciences” Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.