Functional Hair Follicle Regeneration

This document discusses the potential for hair follicle regeneration therapy and the challenges of hair loss treatment. The authors successfully developed fully functional hair regeneration via intracutaneous transplantation of a bioengineered hair follicle germ, which was reconstituted from adult hair follicle-derived stem cells using their developed organ germ method. The paper concludes by discussing the potential of organ regenerative therapy for the medical cure of alopecia. The study provides evidence for the regeneration of a fully functional human hair follicle using bioengineering, which is applicable to human-derived cells and contributes to future developments in hair follicle regenerative medicine.