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This study found no clinically significant effects of intraovarian injection of platelet-rich plasma on ovarian function over one year in patients with extremely low functional ovarian reserve.

In this study, researchers developed an emulgel formulation containing minoxidil for hair growth, using chitosan and fucoidan as gelling agents, achieving controlled drug release with 99.7% released by the 12th hour.

In this study, researchers developed a new self-administered finasteride delivery system using powder-carrying microneedles that improved hair growth efficacy and addressed safety concerns compared to topical finasteride gel by allowing sustained intradermal release of the drug for three days with a single application.

The research observed that 40-nm self-assembled nanoparticles enhanced minoxidil penetration in hairy guinea pig skin compared to 130-nm nanoparticles, but this size effect was absent in hairless skin.

In this study, researchers found that in hairy guinea pig skin, minoxidil delivered via 40-nm nanoparticles had higher skin penetration than 130-nm nanoparticles, indicating nanoparticle size affects permeation.

This review explores the potential of using genetically-manipulated stem cells as both therapeutic agents and gene delivery vehicles for enhanced wound regeneration, but it reports no new clinical results.

This review discusses recent advances in using nanocarrier-loaded gels for various medical applications and reports no new clinical results, highlighting potential advantages in therapeutic strategies.

In this study, researchers developed a polyherbal hair growth oil using botanical substances and base oils like coconut and castor oil, finding it to be stable, non-irritating, and suggesting potential hair-growing properties through mechanisms such as scalp blood flow improvement and anti-inflammatory effects.

This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.

This study found that a biocomposite microneedle system, which includes selenium nanozyme and hypoxic extracellular vesicles, enhanced hair density and follicle diameter in androgenetic alopecia mice by fighting inflammation, promoting blood vessel growth, reducing reactive oxygen species, and counteracting androgen effects.

In a study using an AGA mouse model, researchers observed that a novel topical gel combining hybrid extracellular vesicles, gold nanoparticles, and finasteride accelerated hair regrowth and improved hair quality more effectively than conventional minoxidil treatment, presenting a promising option with fewer side effects.

This research found that STAR particles, ceramic particles with microneedles, significantly enhance skin permeability and improve the topical delivery of drugs like minoxidil and acyclovir, effectively promoting or inhibiting hair growth without causing skin irritation in ex vivo pig skin and rat models.

This review summarizes recent research on microneedles for alopecia treatment and hair regrowth, noting their potential to improve drug delivery and patient outcomes, but reports no new clinical results.

This review discusses completed and ongoing clinical studies on microneedle-based technologies for cosmetic, therapeutic, and diagnostic applications and reports no new clinical results.

This review summarizes current knowledge on tight junctions in mammalian skin and their role in drug delivery and interaction with other barrier components, but reports no new experimental results.

Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.

This review discusses the advantages, applications, and current trends of dissolving microneedles for drug delivery across various therapeutic areas and reports no new clinical results.

This study found that increasing a drug's lipophilicity and adding ethanol to the donor phase can enhance its delivery to the hair follicle, although the precise transport mechanism remains unclear.

This study found that using a protease-triggered release system enabled effective delivery of a model drug deep within porcine hair follicles, suggesting a new approach for treating skin conditions.

This review highlights the emerging potential of electrospun nanofibers in promoting hair growth for androgenetic alopecia, showcasing their advantages like high porosity and antibacterial activity, and the possibility of integrating active pharmaceuticals.

This study found that transfollicular delivery using surfactant-based nanoparticles significantly enhanced antigen stability and immune response compared to other delivery methods, especially when combined with an adjuvant.

This randomized controlled study reported that combining Ecklonia cava with Diane-35 significantly improved weight, waist circumference, hormonal balance, and inflammation markers in women with polycystic ovary syndrome over three months compared to Diane-35 alone.

This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.

This study concluded that combining cyanoacrylate skin surface stripping with particle-based antigen delivery effectively targets HIV-1 p24 protein to skin cells, supporting its potential for needle-free transcutaneous vaccination.

This review highlights the potential of liposomes and nanofibers to enhance wound healing by allowing controlled drug release and supporting natural healing processes, although regulatory challenges remain for their clinical implementation.

In this study, luteolin-loaded nanoemulsions were shown to promote hair growth similarly to a luteolin solution in organic solvents, offering enhanced stability for follicular delivery.

This study found that the newly developed microarray patches for intradermal delivery of finasteride showed high drug content and significantly improved skin deposition compared to existing methods.

This study reviews recent advancements in microneedles made from PLGA, highlighting their use in delivering vaccines, drugs, and proteins through the skin with minimal invasiveness, and discusses the challenges and future potential of these delivery systems.

This study observed that iontophoresis significantly improved the delivery of minoxidil sulfate to hair follicles compared to passive methods, suggesting potential benefits for alopecia treatment.

This study discusses the potential of thermoresponsive nanogels for improving dermal delivery of therapeutics, highlighting their ability to enhance skin penetration and control drug release with minimal damage to the skin's natural barrier.