Recent Advances in Nanocarrier-Loaded Gels: Which Drug Delivery Technologies Against Which Diseases?

    November 2017 in “ Journal of controlled release
    Marion Pitorre, Henri Gondé, Clotilde Haury, Marwa Messous, Jérémie Poilane, David Boudaud, Erdem Kanber, Glenn Alexis Rossemond Ndombina, Jean‐Pierre Benoit, Guillaume Bastiat
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    TLDR Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
    The document reviewed recent advances in nanocarrier-loaded gels for drug delivery, highlighting their potential in treating various diseases such as cancer, skin conditions, and hair loss. These gels, incorporating nanocarriers like liposomes, micelles, and nanoparticles, demonstrated improved therapeutic efficacy, sustained drug release, and reduced side effects. Specific studies showed enhanced drug delivery and prolonged tumor inhibition in cancer therapy, significant symptom reduction in skin diseases, and increased hair growth in hair loss treatments. Clinical trials and preclinical studies underscored the benefits of these hybrid materials in modifying pharmacokinetic profiles and enhancing localized drug delivery. Despite promising results, challenges such as potential toxicity and the need for biocompatibility were noted.
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