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The study observed that finasteride reduced fertility in male Sprague-Dawley rats by impairing the formation of copulatory plugs, an effect considered specific to rats and not applicable to species without this reproductive feature.

Clinical studies reported that finasteride reduces scalp dihydrotestosterone levels and improves hair growth in men with androgenetic alopecia, supporting its role as a treatment option.

This review discusses various chromatographic methods for analyzing finasteride in biological fluids and provides no clinical findings, focusing on detection techniques for different concentration levels.

This case report describes a 52-year-old man who developed generalized vitiligo two months after stopping finasteride and suggests this may be part of post-finasteride syndrome.

This paper discusses the adverse effects of finasteride, including sexual dysfunction and depression, and suggests that treatment customization based on individual factors like hand preference and sexual orientation could improve outcomes and reduce these side effects.

In this study, exposure to the drug finasteride in Silurana tropicalis significantly increased testosterone levels in liver and testis tissues and altered gene expression related to male reproduction and oxidative stress.

In this study, researchers found that finasteride inhibits progesterone synthesis by blocking cholesterol side-chain cleavage in mouse-derived MA-10 Leydig cells, but this effect may not be evident in human or rat cells.

This case report study presents two instances of post-finasteride syndrome, highlighting the persistence of sexual adverse effects despite discontinuation of the drug, and underscores the need for increased awareness and understanding of this condition.

This study validated a new RP-HPLC method for accurately determining doxazosin mesylate and finasteride in bulk powders and capsule formulations.

Finasteride discontinuation increases sperm count in men.

Pill splitting increased generic finasteride sales but didn't affect branded finasteride sales.

This study found that in male rats, finasteride significantly decreased spermatogonia and primary spermatocytes numbers and increased Leydig cells, but did not affect overall testis histology or spermatogenesis.

Finasteride reduces gambling symptoms in Parkinson's patients.

This study reported that combined oral finasteride and topical 5% minoxidil treatment in men with male-pattern hair loss improved hair growth by initiating anagen in pre-existing but deficient follicles, yet the growth rates remained unchanged and did not normalize hair productivity.

This study optimized and validated a dissolution test method for immediate-release finasteride capsules, highlighting the need for an official standard due to variability in commercial products.

Finasteride helps hair growth.

This study found that finasteride decreased plasma dihydrotestosterone levels and altered steroid metabolism, similar to the profile of male pseudohermaphrodites with inherited 5a-reductase deficiency.

This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.

This study developed and validated an HPLC method to quantify impurities in finasteride, demonstrating its suitability for quality assurance of the drug and its related substances.

In this study, researchers found that finasteride undergoes second-order alkaline degradation kinetics and that its degraded form negatively impacts cell proliferation, highlighting the need for careful handling in pharmaceutical manufacturing and storage.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

This case report discusses a 32-year-old man's treatment for advanced androgenetic alopecia using a combination of topical minoxidil and oral finasteride, but no clinical outcomes are detailed.

This review explores the inconsistent therapeutic effects and side effects of finasteride for androgenic alopecia, highlighting the need for further research to better predict individual patient responses.

This study found that finasteride treatment in male rats altered steroid hormone homeostasis and caused kidney damage, suggesting potential risks for patients with renal dysfunction on androgen or antiandrogen therapy.

This study found that finasteride and melengestrol acetate exhibit varying levels of toxicity to freshwater mussels, amphipods, and mayflies, but current environmental concentrations suggest minimal direct effects on these aquatic invertebrates.

This study used Density Functional Theory-based computational methods to analyze finasteride's molecular properties, finding that the GGA/PW91 method closely matches experimental data for vibrational frequencies and geometric parameters.

This study reported the development of two highly sensitive ELISA assays to detect banned substances finasteride and dutasteride in human urine, offering better sensitivity than existing HPLC/MS/MS methods.

This review explores finasteride's effects on neuroactive steroid levels and their potential influence on disorders like depression and alcohol withdrawal but reports no new clinical findings.

This study found that spironolactone, flutamide, and finasteride are similarly effective in reducing hair diameter and Ferriman-Gallwey scores in women with hirsutism over a 6-month treatment period.

Ethosomes improve finasteride delivery through skin for hair loss treatment.