Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

    September 2018 in “ Journal of Separation Science ”
    Yang Liu, Yanan Zhou, Yandong Dai … Qingsheng Zhang
    Studysummary This study demonstrated that using finasteride impurity as a non-isotopically labeled internal standard in paper spray ionization–mass spectrometry can effectively and efficiently measure finasteride tablet dissolution, achieving results comparable to high-performance liquid chromatography.
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    Research cited in this study 2

    1. Rapid Determination of Finasteride in Human Plasma by UPLC-MS/MS and Its Application to Clinical Pharmacokinetic Study Journal of Chromatography B · 2010
    2. Finasteride Drugs · 1999