Post-Finasteride Adverse Effects in Male Androgenic Alopecia: A Case Report of Vitiligo

    January 2017 in “ Skin Pharmacology and Physiology ”
    Ion G. Motofei, David L. Rowland, Simona Roxana Georgescu, Mircea Tampa, Stana Paunica, Vlad Denis Constantin, Cristian Balalau, Mirela Manea, Bogdan C. Baleanu, Ioanel Sinescu
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    TLDR Finasteride may cause vitiligo, sexual issues, and depression; better treatments and predicting side effects needed.
    A case report discusses a 52-year-old man who developed vitiligo, mild sexual dysfunction, and moderate depressive symptoms after taking finasteride for male androgenic alopecia. The report suggests that further studies should explore therapeutic approaches that not only decrease circulating dihydrotestosterone levels but also block dihydrotestosterone receptors, particularly those with selective tropism towards the skin. Additionally, the possibility of predicting adverse effects of finasteride based on hand preference and sexual orientation should be considered.
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      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 7 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community Saying creatine causes loss on fin/dut makes no sense and this is why

      in Finasteride/Dutasteride  42 upvotes 10 months ago
      The conversation discusses whether creatine causes hair loss for those using finasteride or dutasteride, with some suggesting creatine might increase DHT or upregulate androgen receptors, potentially leading to hair loss. Others argue the evidence is not conclusive, citing limited studies and personal anecdotes, with some avoiding creatine as a precaution.
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      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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