Vibrational Spectroscopic Investigation and Molecular Structure of a 5α-Reductase Inhibitor: Finasteride

    January 2020 in “ Química Nova ”
    Linjie Wang, William J. Zeng, Song Gao
    Studysummary This study used Density Functional Theory-based computational methods to analyze finasteride's molecular properties, finding that the GGA/PW91 method closely matches experimental data for vibrational frequencies and geometric parameters.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on doi.org →
    Discuss this study in the Community →

    Related research 4

    1. A Review on Finasteride: A 5-Alpha Reductase Inhibitor, Its Mechanism, Facts, and Benefits Journal of Drug Delivery and Therapeutics · 2019
    2. Discovery of a Novel Hybrid from Finasteride and Epristeride as 5α-Reductase Inhibitor Bioorganic & Medicinal Chemistry Letters · 2010
    3. A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride Clinical Pharmacology & Therapeutics · 1998
    4. Comparison of Finasteride, a 5α Reductase Inhibitor, and Various Commercial Plant Extracts in In Vitro and In Vivo 5α Reductase Inhibition The Prostate · 1993