8 citations
,
January 2016 in “Evidence-based Complementary and Alternative Medicine” This study found that Rumex japonicus Houtt. root extract promoted hair growth by enhancing cell proliferation and preventing apoptosis in human dermal papilla cells and HaCaT cells, as well as in a mouse model.
8 citations
,
March 2014 in “American Journal of Pathology” This study found that hairless mice with homozygous mutations developed significantly more aggressive basal cell carcinomas and a heightened inflammatory response to UVB exposure compared to their haired littermates.
8 citations
,
May 1996 in “Endocrinology” This study found that the androgen precursors DHEA and androstenedione stimulated androgen-sensitive parameters in the sebaceous glands of the skin in castrated male hamsters.
7 citations
,
November 2022 in “Communications biology” This study found that injecting keratin into the skin of mice promoted hair growth, potentially through keratin's interaction with hair-forming cells and changes in the microenvironment.
7 citations
,
October 2017 in “Artificial Cells Nanomedicine and Biotechnology” This research observed that finasteride-loaded ethosomes showed improved permeation across rat skin and human cadaver scalp skin compared to unencapsulated finasteride, potentially enhancing delivery to hair follicle units.
6 citations
,
March 2019 in “International Journal of Molecular Medicine” This study found that finasteride-loaded microspheres effectively treated androgenic alopecia in a mouse model, showing similar hair growth effects to orally-administered finasteride.
6 citations
,
March 2018 in “Journal of Medicinal Food” This study demonstrated that water-soluble peptides from egg yolk, termed "hair growth peptide," stimulated human hair follicle cell growth and improved hair growth in female pattern hair loss.
6 citations
,
September 2012 in “Aesthetic Plastic Surgery” This study found that prolonged topical application of minoxidil significantly increased skin flap survival in rats by promoting angiogenesis compared to shorter application or a saline control.
6 citations
,
July 2009 in “Biomolecules & therapeutics” This study found that combining MSM with MAP significantly enhanced hair growth in mice, comparable to or better than minoxidil, due to increased intradermal retention of MAP.
6 citations
,
March 1999 in “Journal of pediatric health care” This article reviews the anatomical and physiological characteristics of African American hair and skin, discusses common disorders and their management, but reports no new clinical findings.
5 citations
,
June 2022 in “Frontiers in immunology” This study observed that expanding regulatory T cells in the skin of mice with alopecia areata did not reverse the condition, indicating that additional immunotherapy may be necessary.
5 citations
,
January 2017 in “Laboratory Animal Research” This study observed that gold thread implantation increased hair regrowth in both human patients and mice, suggesting it could be an effective hair regrowth treatment, although further studies are needed to understand its mechanisms and safety.
5 citations
,
December 2011 in “Drug Research” This study found that cortexolone 17α-propionate showed strong topical antiandrogenic activity, outperforming progesterone and several known antiandrogens, but lacked systemic antiandrogenic effects in animal models.
5 citations
,
January 2011 in “Korean Journal of Pharmacognosy” This study found that Cornus officinalis fermented with Lactobacillus rhamnosus enhanced hair regrowth in mice, outperforming a minoxidil control.
5 citations
,
February 2008 in “Experimental Dermatology” In this study, topical application of Cyclosporin A on mice skin induced hair growth by transitioning follicles from telogen to anagen, but no effect was observed on cultured human hair follicles.
5 citations
,
May 2005 in “Seminars in Plastic Surgery” This article reviews the use of micrografts and minigrafts for facial and scalp hair reconstruction, noting it is safe, predictable, and achieves high patient satisfaction, but it presents no new clinical data.
4 citations
,
August 2025 in “Scientific Reports” This study found that hair analysis is an effective non-invasive method for assessing metabolic fluctuations, showing stable advanced glycation end products levels that correlate with age and differ significantly between diabetic and non-diabetic rats.
4 citations
,
September 2020 in “Frontiers in Microbiology” In this study, algal oligosaccharides effectively countered key factors in androgenetic alopecia pathogenesis, improving hair growth indicators in vitro and in mice.
4 citations
,
November 2016 in “International Society of Hair Restoration Surgery” This article discusses the progress of follicular unit extraction (FUE) over the past 15 years but reports no new research findings.
4 citations
,
June 2013 in “Aesthetic Plastic Surgery” This study found that minoxidil pretreatment in rat skin flaps enhanced angiogenesis and increased flap survival compared to untreated flaps, but was less effective at reducing necrosis than surgical delay.
4 citations
,
January 2011 This study found that Pleuropterus cilinervis extracts and animal milk fermented with Lactobacillus rhamnosus promoted hair growth in mice, suggesting potential applications in hair loss treatments.
3 citations
,
November 2022 in “Frontiers in molecular biosciences” This study suggests that in mice, plasmalogens may enhance hair growth by activating TRPC4 channels, which increases calcium influx and subsequently stimulates AMPK in hair follicles.
3 citations
,
January 2021 in “Applied sciences” This study found that in C57BL/6 mice, treatment with fermented red ginseng marc, a traditional polyherb formula, or a combination of both, promoted hair growth by enhancing the hair-growth cycle.
3 citations
,
January 2021 in “Journal of Bioscience and Bioengineering” In this study, researchers found that sweet potato shochu oil promotes hair growth in both human follicle dermal papilla cells and C3H mice. The oil contains components like ethyl palmitate, ethyl linoleate, and ethyl α-linolenate, which were key contributors to its hair growth-inducing effects.
3 citations
,
September 2020 This study found that the medication dyclonine has a potent inhibitory effect on the TRPV3 channel, effectively rescuing cell death and alleviating pruritus symptoms in a mouse model with gain-of-function TRPV3 mutations, suggesting potential for treating skin inflammation.
3 citations
,
October 2019 in “Pharmaceutics” This study suggests that newly developed micro-pigment-encapsulated biodegradable microneedles accurately implant pigments in pig cadaver skin, potentially advancing scalp micro-pigmentation methods.
3 citations
,
July 2019 in “International journal of scientific research in science and technology” This study found that a herbal gel containing fenugreek seed extract significantly promoted hair growth on mice after 30 days of topical application.
3 citations
,
April 2014 in “Journal of Dietary Supplements” This study found that CARI ONE, a herbal mixture, promotes hair growth in mice by inducing the transition from telogen to anagen phase and enhancing hair follicle development, compared to control and minoxidil treatments.
3 citations
,
July 2013 in “Bioscience, Biotechnology, and Biochemistry” This study found that topically applied Chinese black tea extract, when fermented and combined with capsaicin, significantly promoted hair growth in mice, potentially involving estrogen receptor interactions.
3 citations
,
January 2005 in “Biological & Pharmaceutical Bulletin” This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.