Gold Thread Implantation Promotes Hair Growth in Humans and Mice

    January 2017 in “ Laboratory Animal Research
    Jong-Hwan Kim, Eunyoung Cho, Euna Kwon, Woo Ho Kim, Jin‐Sung Park, Yong-Soon Lee, Jun-Won Yun, Byeong‐Cheol Kang
    From the encyclopedia
    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

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    Studysummary This study observed that gold thread implantation increased hair regrowth in both human patients and mice, suggesting it could be an effective hair regrowth treatment, although further studies are needed to understand its mechanisms and safety.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    In a 2017 study, researchers discovered that gold thread implantation could effectively promote hair regrowth in both humans and mice. A 38-year-old female patient experienced increased hair growth 24 months after undergoing a facial lifting procedure that included gold thread implantation, without any hair growth medications. In mice, the implantation of gold threads resulted in a significant increase in the number of hair follicles by day 14 post-implantation, outperforming the results seen with a polyglycolic acid (PGA) thread group. Histological analysis showed stronger PCNA staining and higher collagen density in the skin of gold thread-implanted mice, indicating enhanced hair follicle development. The study, which included 19 mice per group, suggests that gold thread implantation could be a viable alternative therapy for hair loss, offering a potential substitute for FDA-approved drugs like finasteride and minoxidil, which can have adverse effects. However, further research is necessary to confirm the therapeutic mechanisms and assess long-term safety.
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