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Activating Notch signaling can kill basal cell carcinoma cells.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.

PRP and PRF show promise for hair growth but need more research for consistent and safe use.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Dermal macrophages might help regrow hair.

Two mouse mutations cause similar hair loss despite different skin changes.

Aging slows wound healing due to weaker cells and immune response.

Macrophage iron release is crucial for hair growth and wound healing.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

PRP shows promise in musculoskeletal rehabilitation but needs standardized reporting for better outcomes.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.

Blocking certain immune signals can reduce skin damage from radiation therapy.

The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.

Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.

The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.