Image

    Implanted Hair-Follicle-Associated Pluripotent Stem Cells Aid Wound Healing and Reduce Scarring in Mice

    August 2022 in “ Research Square (Research Square) ”
    Koya Obara, Kyoumi Shirai, Yuko Hamada … Yasuyuki Amoh

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that implanting HAP stem cells in a mouse model accelerated wound closure and reduced scar formation, suggesting potential for scar-free wound healing.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on researchsquare.com →
    Discuss this study in the Community →

    Research cited in this study 8

    1. Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis Bone Research · 2018
    2. Advances of Stem Cell Therapeutics in Cutaneous Wound Healing and Regeneration Mediators of Inflammation · 2017
    3. Isoproterenol Directs Hair Follicle-Associated Pluripotent (HAP) Stem Cells to Differentiate In Vitro to Cardiac Muscle Cells Which Can Be Induced to Form Beating Heart-Muscle Tissue Sheets Cell cycle/Cell cycle (Georgetown, Tex. Online) · 2016
    4. From Hair to Heart: Nestin-Expressing Hair-Follicle-Associated Pluripotent Stem Cells Differentiate to Beating Cardiac Muscle Cells Cell Cycle · 2015
    5. Multipotent Nestin-Expressing Stem Cells Capable of Forming Neurons Are Located in the Upper, Middle, and Lower Part of the Vibrissa Hair Follicle Cell Cycle · 2012
    6. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    7. Nascent Blood Vessels in the Skin Arise from Nestin-Expressing Hair-Follicle Cells Proceedings of the National Academy of Sciences · 2004
    8. Nestin Expression in Hair Follicle Sheath Progenitor Cells Proceedings of the National Academy of Sciences · 2003

    Related research 5

    1. Implanted Hair-Follicle-Associated Pluripotent Stem Cells Aid Wound Healing and Reduce Scarring in Mice Research Square (Research Square) · 2022
    2. Hedgehog Signaling in Papillary Fibroblasts Is Essential for Hair Follicle Regeneration During Wound Healing Journal of Investigative Dermatology · 2021
    3. Skin Structure and Function, Wound Healing and Scarring Elsevier eBooks · 2021
    4. Regeneration of Dermis: Scarring and Cells Involved Cells · 2019
    5. Epithelial Stem Cells And Implications For Wound Repair Seminars in Cell & Developmental Biology · 2012