Search

for
Search:

GlossaryCOL1A2

gene encoding part of type I collagen, crucial for connective tissues

COL1A2 is a gene that encodes for the alpha-2 chain of type I collagen, which is a crucial protein in the human body. Type I collagen is the most abundant collagen and is essential for the strength and structure of connective tissues, including skin, bones, and tendons. Mutations in the COL1A2 gene can lead to various connective tissue disorders, such as osteogenesis imperfecta, which is characterized by brittle bones.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 292 results

research Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase I Study

6 citations, September 2019 in “Skin pharmacology and physiology”

RCS-01 therapy is safe and may improve skin structure by affecting gene expression.

Genome Array on Differentially Expressed Genes of Skin Tissue in Cashmere Goat at Early Anagen of Cashmere Growth Cycle Using DNA Microarray

research Genome Array on Differentially Expressed Genes of Skin Tissue in Cashmere Goat at Early Anagen of Cashmere Growth Cycle Using DNA Microarray

4 citations, October 2014 in “Journal of Integrative Agriculture”

Researchers found 24 genes that change significantly and affect cashmere growth in goats; this could help increase cashmere production.

research Implanted Hair-Follicle-Associated Pluripotent Stem Cells Aid Wound Healing and Reduce Scarring in Mice

August 2022 in “Research Square (Research Square)”

Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.

Minoxidil Exerts Different Inhibitory Effects on Gene Expression of Lysyl Hydroxylase 1, 2, and 3: Implications for Collagen Cross-Linking and Treatment of Fibrosis

research Minoxidil Exerts Different Inhibitory Effects on Gene Expression of Lysyl Hydroxylase 1, 2, and 3: Implications for Collagen Cross-Linking and Treatment of Fibrosis

38 citations, June 2005 in “Matrix Biology”

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

research Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter on Human Dermal Fibroblasts

68 citations, September 2018 in “International Journal of Molecular Sciences”

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

View more "col1a2" in research →

Community Join

2 / 2 results

community DUPA, Non Responders and Connective Tissue Disorders

in Research/Science 7 upvotes 2 months ago

A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

community What should I expect from dutasteride?

in Finasteride/Dutasteride 2 upvotes 4 years ago

The user tried Minoxidil, PRP, Hair Carboxytherapy, and topical Dutasteride with limited success and is now on oral Dutasteride. They are experiencing some hair loss reduction but no significant density improvement, leading to feelings of depression.