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    Glossary COL1A1

    gene encoding type I collagen, vital for connective tissue

    COL1A1 is a gene that provides instructions for making part of a protein called type I collagen, which is crucial for the strength and structure of connective tissues like skin, bone, and tendons. Mutations in this gene can lead to disorders such as osteogenesis imperfecta, which is characterized by brittle bones.

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    Research 10 of 872

    1. Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis Science · 2016 · 242 citations
    2. Expression of anti-aging type-XVII collagen (COL17A1/BP180) in hair follicle-associated pluripotent (HAP) stem cells during differentiation Tissue & Cell · 2019 · 11 citations
    3. Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis Journal of Dermatological Science · 2017 · 8 citations
    4. Restoration of Hair Luster via Novel Biomarker COL7A1 by Minoxidil, Caffeine, and Biotin Current Issues in Molecular Biology · 2025
    5. 688 Precise and efficient editing of the COL7A1 gene in RDEB derived iPSCs with CRISPR/Cas9 and prime editing Journal of Investigative Dermatology · 2024
    6. An <i>mTurq2-Col4a1</i> mouse model allows for live visualization of mammalian basement membrane development 2023
    7. 244 Defective maintenance of hair follicle stem cells through COL17A1 loss orchestrates the hair follicle aging program Journal of Investigative Dermatology · 2017
    8. Generating LacZ-reporter transgenic mice to identify α1 (XIX) Collagen (Col19a1) expression in Dermal Papilla Cells Benha Veterinary Medical Journal · 2016
    9. A Window into Mammalian Basement Membrane Development: Insights from the<i>mTurq2-Col4a1</i>Mouse Model bioRxiv (Cold Spring Harbor Laboratory) · 2023
    10. Three Novel Homozygous Point Mutations and a New Polymorphism in the COL17A1 Gene: Relation to Biological and Clinical Phenotypes of Junctional Epidermolysis Bullosa The American Journal of Human Genetics · 1997 · 80 citations
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