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In this study, the first case of a persistent curly hair phenotype was reported with nivolumab treatment in a patient with metastatic squamous cell lung cancer.

This study reports that adipose mesenchymal stem cell-derived exosomes and platelet-rich plasma both improved the condition of photoaged facial skin, with no significant difference in effectiveness between the two treatments, potentially offering a quicker and less invasive option for patients.

This study found that biglycan, a protein secreted by dermal papilla cells, plays a critical role in hair follicle cycle regulation and regeneration in mice by activating the Wnt/β-catenin signalling pathway, suggesting its potential as a treatment target for hair loss.

This case report describes a man's permanent skin and hair whitening, and generalized anhidrosis following allogeneic stem cell transplant, linked to immune-mediated destruction of melanocytes.

This abstract outlines the current understanding of cutaneous squamous cell carcinoma (cSCC), identifying it as the second most common non-melanoma skin cancer with risk factors like UV exposure and immunosuppression. It highlights cSCC's potential to metastasize and become fatal, affecting 2%-5% of in situ cases.

This study describes a new method using near infrared femtosecond laser pulses to precisely ablate individual cells in the Drosophila epidermis and peripheral nervous system without damaging surrounding tissues, allowing for detailed observation of cellular responses post-ablation.

This study found that dexamethasone treatment inhibited the inflammatory response and the induction of ornithine decarboxylase activity in mouse skin after TPA application, although the effect on ODC was weaker during the hyperplastic stage.

This study found that overexpression of miR-1246 in peripheral CD4+ T cells can reduce markers associated with inflammation and T cell activation in severe active alopecia areata, suggesting potential therapeutic benefits.

This trial found that intradermal injections of the Hair Stimulating Complex were well-tolerated and effectively stimulated hair growth and prevented hair loss in male pattern baldness participants over 18 weeks.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

This study found that the Foxn1(-/-) nude phenotype significantly influences epithelial progeny in skin, with notable changes in stem cell niches not achievable in other models.

In this study, researchers found that cochlear hair cell function declined with age in CBA/CaJ mice starting at 10 months, before detectable hearing loss, and was marked by a decrease in cell size and BK channel currents, without effect on MET currents.

This study found that para-phenylenediamine induces cytotoxic effects in normal human hair dermal papilla cells by altering microRNA expression and causing cell death, cell cycle arrest, and oxidative stress.

In this study, researchers developed injectable micropore-forming hydrogels that enhance tissue adhesion strength and promote wound healing by allowing better cell infiltration and inducing hair follicle regeneration in skin incision wound models.

Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.

This study introduced a new technique, 2Phatal, enabling precise apoptotic cell ablation in living animals, revealing unique cell-type differences in apoptosis-related dynamics.

Human epidermal stem cells divide faster than previously thought.

This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.

This study found that WNT10A is significantly upregulated in human esophageal squamous cell carcinoma and is associated with enhanced tumor cell migration, invasion, and poor survival.

This study found that dermal sheath stem cell characteristics are lost with aging in humans, affecting skin rejuvenation and structure, and identified specific proteins like Activin A influencing keratinocyte and fibroblast activity.

This study found that all-trans and 9-cis retinoic acids increase steroid sulfatase activity in HL60 cells through mechanisms involving RARα/RXR heterodimers and multiple signaling pathways.

This study found that Phaeodactylum tricornutum extract enhanced hair follicle cell proliferation, indicated by increased keratin and ERK1/2 signaling, suggesting its potential for hair care applications.

This study found that a phosphodiesterase 3 inhibitor promoted hair growth in human dermal papilla cells and stimulated anagen induction in mice, suggesting potential as a treatment for alopecia.

This study suggests that biallelic loss of the Hedgehog signaling repressor Patched alone in Keratin 5+ epidermal cells is insufficient to drive basal cell carcinoma development unless exogenous stimuli trigger accumulation of BCC precursor cells.

This study found that overexpression of the metabolic enzyme PHGDH can promote cancer initiation and progression, highlighting its significant role in tumor cell proliferation and tumorigenesis.

This study found that dysregulation of the DNA damage response in stem cells is a common factor of aging, affecting tissues like the skin, brain, kidneys, and intestine.

This study reports that hair regeneration in live mice involves spatially regulated stem cell divisions and requires mesenchymal interactions, observed in real-time using a novel non-invasive imaging method.

This study found that paclitaxel poliglumex showed limited effectiveness and was relatively well tolerated in post-menopausal women with advanced NSCLC, suggesting further testing of this treatment may not be justified.