Thymic Stromal Lymphopoietin Controls Hair Growth

    February 2022 in “ Stem cell reports ”
    Jessica Shannon, David L. Corcoran, John Murray … Jennifer Zhang
    Studysummary This study found that thymic stromal lymphopoietin (TSLP) promotes hair growth after skin injury by enhancing the proliferation of specific stem cells in hair follicles.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 27

    1. Wound-Induced Hair Neogenesis: A Novel Paradigm for Studying Regeneration and Aging Frontiers in Cell and Developmental Biology · 2020
    2. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts During Wound Healing Cell stem cell · 2020
    3. Through the Lens of Hair Follicle Neogenesis: A New Focus on Mechanisms of Skin Regeneration After Wounding Seminars in Cell & Developmental Biology · 2019
    4. Noncoding dsRNA Induces Retinoic Acid Synthesis to Stimulate Hair Follicle Regeneration via TLR3 Nature Communications · 2019
    5. Injury Modifies the Fate of Hair Follicle Dermal Stem Cell Progeny in a Hair Cycle-Dependent Manner Experimental dermatology · 2019
    6. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    7. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations During Wound Healing Cell Reports · 2018
    8. Macrophages Promote Wound-Induced Hair Follicle Regeneration in a CX3CR1- and TGF-β1-Dependent Manner Journal of Investigative Dermatology · 2018
    9. Microneedling for the Treatment of Hair Loss Journal of The European Academy of Dermatology and Venereology · 2017
    10. Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices Cell · 2017
    11. Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF Nature Communications · 2017
    12. Hair Camouflage: A Comprehensive Review International Journal of Women's Dermatology · 2017
    13. Hair Camouflage: A Comprehensive Review International Journal of Women's Dermatology · 2016
    14. To Control Site-Specific Skin Gene Expression, Autocrine Mimics Paracrine Canonical Wnt Signaling and Is Activated Ectopically in Skin Disease American Journal of Pathology · 2016
    15. dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration Cell Stem Cell · 2015
    16. Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations Cell · 2015
    17. Plasticity of Epithelial Stem Cells in Tissue Regeneration Science · 2014
    18. Spatial Organization Within a Niche as a Determinant of Stem-Cell Fate Nature · 2013
    19. Fgf9 From Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding Nature Medicine · 2013
    20. Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis Through the Receptor Gpr44 Journal of Investigative Dermatology · 2012
    21. A Family Business: Stem Cell Progeny Join the Niche to Regulate Homeostasis Nature Reviews Molecular Cell Biology · 2012
    22. Genome-Wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage Cell stem cell · 2011
    23. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    24. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    25. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    26. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    27. Growth of the Hair Physiological Reviews · 1954

    Related research 1

    1. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018