research Development, Characterization, and Use of a Fetal Skin Cell Bank for Tissue Engineering in Wound Healing
Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.
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research Roles of Jumonji and Jumonji Family Genes in Chromatin Regulation and Development
Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
research Rhamnose-Mediated Modulation of Hair Follicle Growth: Insights from Chemical Genomics
Rhamnose may help hair growth and pigmentation, making it a potential treatment for hair loss.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice
A special stem cell fluid can speed up wound healing and hair growth in mice.
research Regulation of VDR by ΔNp63α Is Associated with Inhibition of Cell Invasion
ΔNp63α helps control a protein that stops cancer cells from spreading.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Establishment of an In Vitro Organoid Model of Dermal Papilla of Human Hair Follicle
Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
research Native and Engineered Extracellular Vesicles for Wound Healing
Extracellular vesicles show promise for wound healing, but more research is needed to improve their stability and production.
research Nanofiber-Mediated Sequential Photothermal Antibacteria and Macrophage Polarization for Healing MRSA-Infected Diabetic Wounds
The nanofibers effectively treated infected diabetic wounds by killing bacteria and aiding wound healing without toxicity.
research Maintaining Inducibility of Dermal Follicle Cells on Silk Fibroin/Sodium Alginate Scaffold for Enhanced Hair Follicle Regeneration
Scaffold improves hair growth potential.
research Epidermal Stem Cells: An Update on Their Potential in Regenerative Medicine
Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Quantitative Proteomic Analysis of Dermal Papilla from Male Androgenetic Alopecia Comparing Before and After Treatment with Low-Level Laser Therapy
Low-level laser therapy improves hair growth and dermal papilla cell function.
research Fibromodulin Reduces Scar Formation in Adult Cutaneous Wounds by Eliciting a Fetal-Like Phenotype
Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
research Oxygen, Metabolism, and Regeneration: Lessons from Mice
Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.
research TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition
The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
research Integrin Signaling Regulates YAP/TAZ to Control Skin Homeostasis
YAP and TAZ are crucial for skin cell growth and repair.
research Follicular Cell Implantation: An Emerging Cell Therapy for Hair Loss
Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging
Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
research Engineering the Niche for Hair Regeneration: A Critical Review
Further research is needed to improve hair regeneration using stem cells and nanomaterials.
research The Genetically Programmed Hair Growth Cycle And Alopecia: What Is There To Know?
The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
research An In Vivo Mouse Excisional Wound Model of Scarless Healing
The mouse model shows potential for understanding and improving scarless wound healing, and Wnt-4 and TGF-β1 play a role in wound healing and scar formation.
research Ficoll Density Gradient Sedimentation Isolation of Pelage Hair Follicle Mesenchymal Stem Cells From Adult Mouse Back Skin: A Novel Method for Hair Follicle Mesenchymal Stem Cells Isolation
A new method quickly and efficiently isolates hair follicle stem cells from adult mice, promoting hair growth.
research Genetically Null Mice Reveal a Central Role for Epidermal Growth Factor Receptor in the Differentiation of the Hair Follicle and Normal Hair Development
EGFR is essential for normal hair development and follicle differentiation.
research Interpretation Of The Yak Skin Single-Cell Transcriptome Landscape
The study mapped yak skin cells to understand hair growth better.
research Ptch2 Is a Potential Regulator of Mesenchymal Stem Cells
Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation
Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.