Regulation of VDR by ΔNp63α Is Associated with Inhibition of Cell Invasion

    July 2009 in “ Journal of Cell Science ”
    Ramakrishna Kommagani, Mary K. Leonard, S. Patrick Lewis … Madhavi Kadakia
    Studysummary This study found that ΔNp63α directly regulates VDR expression, which in turn may reduce invasiveness in an epidermoid cancer cell line.
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    Research cited in this study 3

    1. Vitamin D Receptor Is Essential For Normal Keratinocyte Stem Cell Function Proceedings of the National Academy of Sciences · 2007
    2. Evidence for 1,25-Dihydroxyvitamin D3-Independent Transactivation by the Vitamin D Receptor Journal of biological chemistry/˜The œJournal of biological chemistry · 2007
    3. Lack of the Vitamin D Receptor Is Associated with Reduced Epidermal Differentiation and Hair Follicle Growth ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002