Quantitative Proteomic Analysis of Dermal Papilla from Male Androgenetic Alopecia Comparing Before and After Treatment with Low-Level Laser Therapy

March 2019 in “ Lasers in Surgery and Medicine ”

Ratchathorn Panchaprateep, Trairak Pisitkun, Nuttiya Kalpongnukul

low-level laser therapy dermal papilla androgenetic alopecia quantitative proteomic analysis hair growth DP cell function LLLT DP cells AGA

Studysummary This study found that low-level laser therapy increased the expression of proteins in dermal papilla tissues, suggesting it promotes hair growth in male androgenetic alopecia patients.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This study analyzed the effects of low-level laser therapy (LLLT) on dermal papilla (DP) cells in male androgenetic alopecia (AGA). The researchers used quantitative proteomic analysis to compare the protein expression in DP cells before and after LLLT treatment. They found that LLLT increased the expression of several proteins related to hair growth and DP cell function. The study suggests that LLLT can be a beneficial therapeutic option for AGA. However, the study had a small number of subjects, and further investigations are needed to support the hypothesis.

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