In Silico Analysis of Gene Expression Data from Bald Frontal and Haired Occipital Scalp to Identify Candidate Genes in Male Androgenetic Alopecia

    September 2019 in “ Archives of Dermatological Research ”
    A. Premanand, B. Reena Rajkumari
    Studysummary In this study, researchers identified 32 differentially expressed genes involved in androgenetic alopecia, with down-regulated genes associated with Wnt and TGF-beta signaling and up-regulated genes linked to oxidative stress pathways.
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    Research cited in this study 25

    1. Androgen Modulation of Wnt/β-Catenin Signaling in Androgenetic Alopecia Archives of Dermatological Research · 2018
    2. Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles Journal of Investigative Dermatology · 2017
    3. Genome-Wide Gene Expression Dataset Used to Identify Potential Therapeutic Targets in Androgenetic Alopecia Data in Brief · 2017
    4. Psychosocial Aspects of Hair Loss InTech eBooks · 2017
    5. Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways British Journal of Dermatology · 2017
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    7. Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia Expert Opinion on Therapeutic Targets · 2014
    8. Premature Graying as a Consequence of Compromised Antioxidant Activity in Hair Bulb Melanocytes and Their Precursors PLOS ONE · 2014
    9. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    10. Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis Through the Receptor Gpr44 Journal of Investigative Dermatology · 2012
    11. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    12. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    13. Identification of the C-Terminal Tail Domain of AHF/Trichohyalin as the Critical Site for Modulation of the Keratin Filamentous Meshwork in the Keratinocyte Journal of Dermatological Science · 2011
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    18. Profiling the Response of Human Hair Follicles to Ultraviolet Radiation Journal of Investigative Dermatology · 2009
    19. Oxidative Stress in Aging of Hair International Journal of Trichology · 2009
    20. Progression of Hair Loss in Men With Androgenetic Alopecia: Long-Term Controlled Observational Data in Placebo-Treated Patients 2008
    21. Specific Citrullination Causes Assembly of a Globular S100A3 Homotetramer Journal of biological chemistry/˜The œJournal of biological chemistry · 2007
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    25. The Psychosocial Consequences of Androgenetic Alopecia: A Review of the Research Literature British Journal of Dermatology · 1999

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    1. In Silico Analysis of Gene Expression Data from Bald Frontal and Haired Occipital Scalp to Identify Candidate Genes in Male Androgenetic Alopecia Archives of Dermatological Research · 2019