Ptch2 Is a Potential Regulator of Mesenchymal Stem Cells

    April 2022 in “ Frontiers in Physiology ”
    Emma Juuri, Pauli Tikka, Andrii Domanskyi … Anamaria Balic
    Studysummary This study found that loss of the Ptch2 receptor in mice leads to increased incisor growth and enhanced mesenchymal stem cell differentiation, highlighting Ptch2's role in organ regenerative potential.
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    Research cited in this study 6

    1. Dental Cell Type Atlas Reveals Stem and Differentiated Cell Types in Mouse and Human Teeth Nature Communications · 2020
    2. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    3. Defining Stem Cell Dynamics and Migration During Wound Healing in Mouse Skin Epidermis Nature Communications · 2017
    4. Palatogenesis and Cutaneous Repair: A Two-Headed Coin Developmental Dynamics · 2014
    5. The Hair Cycle Journal of Cell Science · 2006
    6. The Hair Cycle Journal of Cell Science · 2006

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