127 citations
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January 2015 in “Journal of Biological Rhythms” This review discusses the role of the circadian clock in skin functions such as cell proliferation and UV protection and reports no new results; the authors note its potential in studying immune regulation and seasonal behaviors.
September 2017 in “Journal of Investigative Dermatology” Certain products and treatments can improve hair health and growth.
24 citations
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October 2017 in “Scientific reports” This study suggests that controlling light exposure can influence cashmere growth by triggering hair follicles to enter their active growth phase sooner, potentially involving the CSDC2 gene as a key regulator.
16 citations
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September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that the retinol dehydrogenases SDR16C5 and SDR16C6 in mice play a crucial role in skin retinol dehydrogenase activity, affecting hair growth and gland functions without impacting survival.
1 citations
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August 2023 in “Journal of cutaneous pathology” This case report describes an 8 cm giant pilomatricoma on a 67-year-old man's scalp, revealing distinct transcriptional patterns related to hair follicle factors and keratin through spatial gene expression analysis.
236 citations
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July 2001 in “Trends in Molecular Medicine” This review discusses common hair loss conditions and explores how advancements in hair follicle biology might lead to more effective treatments but reports no new results.
115 citations
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August 2008 in “The Journal of Clinical Endocrinology & Metabolism” In this study, T3 and T4 were found to directly influence human hair follicles in vitro, enhancing keratinocyte proliferation, prolonging the hair growth phase, and affecting pigmentation.
47 citations
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March 2019 in “Journal of immunology research” This review discusses the effects of valproic acid on immune cell activation and gene expression, potentially influencing infection outcomes and suggesting its promise for autoimmune and hypersensitivity condition management.
28 citations
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March 2019 in “Journal of Dermatological Science” This review discusses methods for evaluating hair growth-promoting effects of candidate substances for androgenetic alopecia, focusing on cell assays, organ cultures, and animal models, and reports no new results.
20 citations
,
June 2014 in “BMC genomics” This study identified the placenta at the base of the ovary as the origin of poplar seed hair development and detailed transcriptome dynamics during the growth process.
19 citations
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April 2015 in “Developmental Dynamics” This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.
1 citations
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June 2018 in “World rabbit science” This study identified differentially expressed microRNAs between back and belly skin in Rex rabbits, highlighting their potential roles in skin development processes.
1 citations
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February 2018 in “Madridge journal of dermatology & research” In this study, Satura® Rosta remedy was found to significantly increase hair follicle size, hair root volume, and skin thickness in mice, potentially by prolonging the anagen phase, with notable hair regrowth observed in older mice with alopecia.
November 2023 in “PubMed” In this study using animal models, umbilical cord stem cell conditioned media combined with oral anti-androgens improved hair regeneration in androgenetic alopecia, enhancing hair follicle cycles and reducing inflammation, suggesting potential as a promising therapy.
The study found that adipose-derived mesenchymal stem cells obtained via laser-assisted liposuction with selective photo-stimulation are comparable in differentiation potential and tumorigenic risk to those from conventional liposuction for cell therapy applications.
March 2014 in “Chinese Journal of Dermatology” This study found that dermal papilla cells from different scalp regions of AGA patients showed differential gene expression related to cell proliferation, apoptosis, and signaling pathways when exposed to DHT in a 3D culture.
86 citations
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October 2005 in “Experimental Dermatology” This review explores the role of Foxn1 in mammalian skin biology, discussing its influence on hair follicle function and the potential for further research to enhance understanding of epithelial differentiation.
2 citations
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June 2001 in “American Journal of Pathology” This article explores the complexity and significance of the hair follicle, emphasizing new insights into its biological roles and the involvement of p53 in follicular regression.
April 2012 in “Cancer Research” In this study, mouse models with EGFR deficiency showed that disrupted hair follicle cycling leads to increased mast cell numbers and inflammation, suggesting EGFR's role in managing hair cycle transitions and preventing folliculitis.
224 citations
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March 2006 in “Seminars in Cutaneous Medicine and Surgery” This article discusses the hair follicle's regenerative cycles and the molecular mechanisms influencing them, emphasizing the need for therapeutic targeting of the "hair cycle clock" to manage hair growth disorders, without reporting new research findings.
65 citations
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January 2018 in “Nature Reviews Endocrinology” This review discusses the unique features of dermal white adipose tissue, its interaction with hair follicles, and its role in skin physiology, reporting no new experimental findings.
15 citations
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December 2020 in “International journal of molecular sciences” This review explores how epidermal stem cells contribute to the development and maintenance of various skin structures, and highlights specific markers and proteins associated with these cells, but reports no new clinical results.
11 citations
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March 2001 in “Clinics in dermatology” This study found that using a novel dissolving microneedle with valproic acid effectively enhances hair follicle regrowth through improved delivery and activation of the Wnt/β-catenin pathway compared to topical application.
37 citations
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February 2019 in “Experimental Dermatology” This study explored the regenerative abilities of the African spiny mouse's skin, revealing more robust wound-induced hair follicle neogenesis compared to laboratory mice and highlighting unique features of its hair and wound response.
36 citations
,
April 2016 in “Biochimie” This study shows that the concentration of epidermal growth factor (EGF) is crucial for determining whether mink hair follicles are promoted or inhibited in vitro, with involvement of the Notch signaling pathway in DP cell proliferation.
1 citations
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May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” This article from the 4th Intercontinental Meeting of Hair Research Societies provides no abstract or new findings.
In this study with mice, simultaneous inactivation of Smad4 and PTEN genes led to rapid development of invasive forestomach squamous cell carcinomas, mirroring human esophageal SCCs.
In this study, the deletion of Smad4 and PTEN genes in mice was associated with rapid and invasive squamous cell carcinoma formation in the forestomach, modeling human esophageal cancer progression.
18 citations
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October 2017 in “PLOS ONE” This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.
13 citations
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June 2020 in “BMC genomics” This study found that chi-miR-30b-5p was more expressed in the telogen phase than in the anagen phase and inhibited dermal papilla cell proliferation by targeting CaMKIIδ.