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The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Mutations in the DSG4 gene cause fragile, sparse hair in humans, mice, and rats.

Overexpression of HDGF in melanocytes does not cause cancer.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Mice genetically modified to produce more Del1 protein had faster hair regrowth.

Ro stress hindered ginseng root growth and ginsenoside production, but increased certain hormones and affected gene regulation related to plant growth and stress responses.

Prostaglandin E2 collagen matrix may help stimulate hair growth.

Vitamin B3 may help prevent hair loss and promote hair growth by protecting scalp cells from stress and reducing hair growth-blocking proteins.

Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.

A protein from fat-derived stem cells, DKK1, is linked to hair loss and blocking it may help treat alopecia areata.

A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.

Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.

Fat cells help recruit healing cells and build skin structure during wound healing.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

Hair follicle regeneration possible, more research needed.

The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.

The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.

ZO-1 helps hair follicle stem cells renew better by changing their structure.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.

New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.