Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity

    November 2023 in “ Advanced Science ”
    Diane S. Kang, Aidan Moriarty, Y. Wang … Meng‐Fei Yu
    Studysummary A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
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    Research cited in this study 2

    1. Hair Keratin KRT81 Is Expressed in Normal and Breast Cancer Cells and Contributes to Their Invasiveness Oncology Reports · 2017
    2. Transcription Regulation and Protein Subcellular Localization of the Truncated Basic Hair Keratin hHb1-ΔN in Human Breast Cancer Cells Journal of Biological Chemistry · 2001

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