research Corneodesmosin Gene Ablation Induces Lethal Skin-Barrier Disruption and Hair-Follicle Degeneration Related to Desmosome Dysfunction
Deleting the CDSN gene causes severe skin and hair problems, leading to death.
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5 / 561 resultsresearch Immunolocalization of Junctional Proteins in Human Hairs Indicates That the Membrane Complex Stabilizes the Inner Root Sheath While Desmosomes Contact the Companion Layer Through Specific Keratins
Junctional proteins stabilize the inner root sheath and connect the companion layer in human hair.
research Desmosomes in Developing Human Epidermis
Desmosomes are crucial for human skin development, increasing in density as the skin matures.
research Imaging Nanoscale Changes in Desmosome Protein Organization
Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.
research Using the Frog Embryonic Epidermis as a Model to Study Desmosome Function During Development
Frog skin cells need the protein desmoplakin for proper development and cell layer formation.
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