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GlossaryDesmosomal Components

proteins and structures that hold cells together in tissues

Desmosomal components are the proteins and structures that make up desmosomes, which are specialized cell junctions that help hold cells together, particularly in tissues that experience a lot of stress, like the skin and heart. These components include desmogleins and desmocollins (types of cadherins), as well as plakoglobin and desmoplakin, which link the cell membrane to the internal cytoskeleton, providing mechanical strength and stability.

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research Intercellular Junctions in Normal Epidermis

2 citations , September 2004 in “Experimental Dermatology”

Desmosomal adhesion is essential for healthy skin structure and function.

research Biology and Genetics of Hair

89 citations , September 2010 in “Annual Review of Genomics and Human Genetics”

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

research Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children

55 citations , October 1992 in “Archives of Dermatology”

Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.

research Recent Advances in Congenital Ichthyoses

10 citations , July 2015 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics”

New genes linked to ichthyosis were found, but there's still no cure; treatment options are improving.

research Molecular Genetics of Alopecias

9 citations , January 2015 in “Current problems in dermatology”

Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.

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