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    Glossary Desmosomal Components

    proteins and structures that hold cells together in tissues

    Desmosomal components are the proteins and structures that make up desmosomes, which are specialized cell junctions that help hold cells together, particularly in tissues that experience a lot of stress, like the skin and heart. These components include desmogleins and desmocollins (types of cadherins), as well as plakoglobin and desmoplakin, which link the cell membrane to the internal cytoskeleton, providing mechanical strength and stability.

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    1. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    2. Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children Archives of Dermatology · 1992 · 55 citations
    3. Congenital hair loss disorders: Rare, but not too rare The Journal of Dermatology · 2011 · 41 citations
    4. Recent advances in congenital ichthyoses 2015 · 10 citations
    5. Molecular Genetics of Alopecias Current problems in dermatology · 2015 · 9 citations
    6. Homozygous Nonsense Mutation in DSC3 Resulting in Skin Fragility and Hypotrichosis 2020 · 8 citations
    7. Dysfunction of keratinocyte adhesion Experimental Dermatology · 2004 · 2 citations
    8. Intercellular junctions in normal epidermis Experimental Dermatology · 2004 · 2 citations
    9. Hair Loss in Autoimmune Cutaneous Bullous Disorders Dermatologic Clinics · 2011 · 12 citations
    10. Novel compound heterozygous mutations in the<i>desmoplakin</i>gene cause hair shaft abnormalities and culminate in lethal cardiomyopathy Clinical and Experimental Dermatology · 2014 · 5 citations
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