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    Glossary Desmoglein

    protein aiding cell adhesion in skin and tissues

    Desmoglein is a type of protein found in the skin and other tissues that helps cells stick together, forming strong connections called desmosomes. These proteins are crucial for maintaining the structural integrity of tissues, and their dysfunction can lead to skin disorders and diseases such as pemphigus, where the skin becomes fragile and blisters easily.

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    Research 10 of 401

    1. Suprabasal Desmoglein 3 Expression in the Epidermis of Transgenic Mice Results in Hyperproliferation and Abnormal Differentiation Molecular and cellular biology · 2002 · 108 citations
    2. Mutations in the Desmoglein 4 Gene Underlie Localized Autosomal Recessive Hypotrichosis with Monilethrix Hairs and Congenital Scalp Erosions Journal of Investigative Dermatology · 2006 · 81 citations
    3. Mutations in the Desmoglein 4 Gene Are Associated with Monilethrix-like Congenital Hypotrichosis 2006 · 74 citations
    4. Expression of Desmoglein 1 Compensates for Genetic Loss of Desmoglein 3 in Keratinocyte Adhesion Journal of Investigative Dermatology · 2002 · 72 citations
    5. The lanceolate hair rat phenotype results from a missense mutation in a calcium coordinating site of the desmoglein 4 gene Genomics · 2004 · 50 citations
    6. A Recurrent Intragenic Deletion in the Desmoglein 4 Gene Underlies Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2004 · 44 citations
    7. Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation Differentiation · 2009 · 35 citations
    8. A Missense Mutation in the Cadherin Interaction Site of The Desmoglein 4 Gene Underlies Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2005 · 33 citations
    9. Differential structural properties and expression patterns suggest functional significance for multiple mouse desmoglein 1 isoforms Differentiation · 2004 · 29 citations
    10. Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity Developmental Biology · 2008 · 28 citations
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