The Hair Loss Encyclopedia

Search

for
Search:

GlossaryDesmoglein 4

protein crucial for hair follicle formation and maintenance

Desmoglein 4 is a protein that plays a crucial role in the formation and maintenance of hair follicles. It is part of the desmosome complex, which helps cells stick together, ensuring the structural integrity of tissues. Mutations in the gene encoding Desmoglein 4 can lead to hair disorders such as localized autosomal recessive hypotrichosis, characterized by sparse and fragile hair.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 406 results

research Desmoglein 4 Is Regulated by Transcription Factors Implicated in Hair Shaft Differentiation

35 citations , August 2009 in “Differentiation”

Desmoglein 4 is controlled by specific proteins that affect hair growth.

research Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature

15 citations , June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

research A Recurrent Intragenic Deletion in the Desmoglein 4 Gene Underlies Localized Autosomal Recessive Hypotrichosis

44 citations , August 2004 in “Journal of Investigative Dermatology”

A gene deletion in DSG4 causes sparse hair in some Pakistani families.

research The Lanceolate Hair Rat Phenotype Results from a Missense Mutation in a Calcium Coordinating Site of the Desmoglein 4 Gene

50 citations , February 2004 in “Genomics”

A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.

Genetics of Alopecia

research Genetics of Alopecia

April 2012 in “Encyclopedia of Life Sciences”

Different genes are linked to various types of hair loss.

View more "desmoglein 4" in research →

Community Join

0 / 0 results

— no results