Intragenic Deletion in the Desmoglein 4 Gene Underlies the Skin Phenotype in the Iffa Credo Hairless Rat

    October 2004 in “ Differentiation ”
    Hisham Bazzi, Ana Kljuic, Angela M. Christiano, Andrey A. Panteleyev
    Studysummary This study identified a large deletion in the desmoglein 4 gene as the genetic basis of the Iffa Credo "hairless" rat's skin phenotype, linking it to lanceolate hair mutations.
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    Research cited in this study 8

    1. A Recurrent Intragenic Deletion in the Desmoglein 4 Gene Underlies Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2004
    2. The Lanceolate Hair Rat Phenotype Results from a Missense Mutation in a Calcium Coordinating Site of the Desmoglein 4 Gene Genomics · 2004
    3. Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables Experimental dermatology · 2001
    4. The Catalog of Human Hair Keratins Journal of Biological Chemistry · 2001
    5. Lanceolate Hair-J (LahJ): A Mouse Model for Human Hair Disorders Experimental dermatology · 2000
    6. Lanceolate Hair (Lah): A Recessive Mouse Mutation with Alopecia and Abnormal Hair ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1996
    7. The Effects of Epilation and Hormones on the Activity of Rat Hair Follicles Journal of Experimental Zoology · 1975
    8. The Endocrine System and Hair Growth in the Rat Journal of Endocrinology · 1942