Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identified a large deletion in the desmoglein 4 gene as the genetic basis of the Iffa Credo "hairless" rat's skin phenotype, linking it to lanceolate hair mutations.

This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.

Inhibiting Bmp signaling disrupts hair growth and differentiation.

Apoptosis in hair follicles varies by growth phase, with TGF-β possibly starting the catagen phase.

This study identified novel compound heterozygous mutations in the DSG4 gene in a Japanese patient with congenital hypotrichosis, suggesting overlap between localized autosomal recessive hypotrichosis and monilethrix.