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    Glossary Desmosomal Components

    proteins and structures that hold cells together in tissues

    Desmosomal components are the proteins and structures that make up desmosomes, which are specialized cell junctions that help hold cells together, particularly in tissues that experience a lot of stress, like the skin and heart. These components include desmogleins and desmocollins (types of cadherins), as well as plakoglobin and desmoplakin, which link the cell membrane to the internal cytoskeleton, providing mechanical strength and stability.

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    Research 30 of 553

    1. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    2. Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children Archives of Dermatology · 1992 · 55 citations
    3. Congenital hair loss disorders: Rare, but not too rare The Journal of Dermatology · 2011 · 41 citations
    4. Recent advances in congenital ichthyoses 2015 · 10 citations
    5. Molecular Genetics of Alopecias Current problems in dermatology · 2015 · 9 citations
    6. Homozygous Nonsense Mutation in DSC3 Resulting in Skin Fragility and Hypotrichosis 2020 · 8 citations
    7. Dysfunction of keratinocyte adhesion Experimental Dermatology · 2004 · 2 citations
    8. Intercellular junctions in normal epidermis Experimental Dermatology · 2004 · 2 citations
    9. Hair Loss in Autoimmune Cutaneous Bullous Disorders Dermatologic Clinics · 2011 · 12 citations
    10. Novel compound heterozygous mutations in the<i>desmoplakin</i>gene cause hair shaft abnormalities and culminate in lethal cardiomyopathy Clinical and Experimental Dermatology · 2014 · 5 citations
    11. 피부 발육과정에서 데스모콜린 1의 발현에 관한 면역조직화학적 연구 대한피부과학회지 · 2012
    12. 14-3-3σ Is Required for Club Hair Retention 2010 · 8 citations
    13. LB1076 Using the frog embryonic epidermis as a model to study desmosome function during development Journal of Investigative Dermatology · 2019
    14. PA05 A rare case of cardiocutaneous syndrome in a young child 2023
    15. Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome The American Journal of Dermatopathology · 2005 · 31 citations
    16. Desmosomes in Developing Human Epidermis Dermatology Research and Practice · 2010 · 11 citations
    17. Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction Journal of Cell Science · 2009 · 87 citations
    18. The Cytology and Cytochemistry of the Wool Follicle International review of cytology · 1979 · 90 citations
    19. Corneodesmosin: Structure, Function and Involvement in Pathophysiology The Open Dermatology Journal · 2010 · 2 citations
    20. A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling iScience · 2023 · 1 citations
    21. <i>DSG4</i> Gene Variants as a Cause of Hypotrichosis in the Child with Severe Atopic Dermatitis: Clinical Case Вопросы современной педиатрии · 2023
    22. FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation Autophagy · 2014 · 60 citations
    23. Melatonin induces a stimulatory action on the scrotal skin components of Soay ram in the non-breeding season Scientific reports · 2020 · 13 citations
    24. A Spontaneous Deletion within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype ˜The œAmerican journal of pathology · 2014 · 11 citations
    25. Ultrastructural Resemblance of Basal Cell Epithelioma to Primary Epithelial Germ Journal of Cutaneous Pathology · 1978 · 47 citations
    26. Patterns of desmocollin synthesis in human epithelia: immunolocalization of desmocollins 1 and 3 in special epithelia and in cultured cells. PubMed · 1996 · 96 citations
    27. Desmoglein 4 Mutations Underlie Localized Autosomal Recessive Hypotrichosis in Humans, Mice, and Rats Journal of Investigative Dermatology Symposium Proceedings · 2005 · 13 citations
    28. Transcriptome Profiling of Pilosebaceous Units in Male Androgenetic Alopecia Reveals Altered Junctional Networks Journal of Investigative Dermatology · 2021
    29. Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse The Journal of Physiology · 2024 · 7 citations
    30. A Recurrent Intragenic Deletion in the Desmoglein 4 Gene Underlies Localized Autosomal Recessive Hypotrichosis Journal of Investigative Dermatology · 2004 · 44 citations