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This study reported that genetic testing is crucial for accurately diagnosing hypotrichosis, especially in cases with subtle symptoms or coexisting severe atopic dermatitis, as demonstrated in a young girl with a DSG4 gene mutation.

This study found that two unrelated domestic shorthair cats had novel DSG4 gene mutations causing defective hair shafts, representing the first report of pathogenic DSG4 variants in domestic animals.

This study found that autophagy is impaired in Birt-Hogg-Dubé syndrome-associated renal tumors and identified that the FLCN protein interacts with key autophagy components regulated by ULK1.

This study found that basal cell epithelioma resembles fetal primary epithelial germ based on specific cellular characteristics.

This study demonstrated that murine monoclonal antibodies can reveal specific patterns of desmosomal cadherin expression, Dsc1 and Dsc3, in human tissues and cultured cells using immunofluorescence microscopy.

This study describes a genetic mutation in the desmoglein 4 gene linked to localized autosomal recessive hypotrichosis in Pakistani families, showing similarities to animal models with similar hair loss conditions.

This study found that specific junctional proteins are significantly downregulated in balding regions of the scalp in men with androgenetic alopecia, suggesting disrupted cell communication may play a role in hair loss.

This study suggests that male sex and androgenic steroid use increase the risk of atrial arrhythmias in individuals with arrhythmogenic right ventricular cardiomyopathy, especially those with desmosomal gene mutations.

A gene deletion in DSG4 causes sparse hair in some Pakistani families.

This study found that bikunin is expressed in human keratinocytes and may play a role in regulating keratinocyte function during mitosis or inflammation.

A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.

This study reported that specific inhibition of the classical complement pathway with BIVV009 prevented C3 deposition along the dermal-epidermal junction in bullous pemphigoid, reflecting its potential efficacy.

This chapter reviews skin components, wound healing mechanisms, and the potential of biomaterials to enhance skin repair and regeneration, without offering new experimental results.

This review summarizes current knowledge on tight junctions in mammalian skin and their role in drug delivery and interaction with other barrier components, but reports no new experimental results.

This study found that the S100A3 gene is exclusively expressed in hair follicle cells differentiating into hair shaft components in mice, suggesting its important role in hair formation.

This study found that human hair follicle dermal cells, specifically dermal sheath cells, can serve as an alternative and potentially superior cell source for constructing the dermal component of bioengineered skin in both in vitro and in vivo settings.

This study compiled an archive of 684 genes associated with monogenic hair disorders, identifying previously unrecognized components of Hippo signaling and proposing a new biologically-grounded disease taxonomy.

This article discusses the potential of induced pluripotent stem cells (iPSCs) for generating skin components, particularly for genetic skin disorder modeling and gene-corrected regenerative therapies, but reports no new clinical results.

This review discusses hair abnormalities in various epidermolysis bullosa subtypes and reports no new clinical findings.

This review discusses the role of traditional Chinese medicine and bioactive materials in chronic wound healing and reports no new clinical results.

This article discusses themes in the molecular structure of hair and reports no new research findings.

This review discusses how neuroendocrine pathways influence keratin regulation in human skin and hair follicles and suggests these pathways as potential targets for new treatments of skin disorders, but reports no clinical results.

In this study, researchers investigated the immunohistopathological characteristics of the skin in individuals during the acute phase of chikungunya infection, revealing CHIKV antigens and inflammatory infiltrates in various skin components and highlighting the role of cytokines/chemokines in the disease's skin manifestations.

The researchers reported that autophagy, a lysosome-dependent degradation mechanism, plays a significant role in the cellular remodeling of keratinocyte differentiation in the skin, affecting the properties of the differentiation products by altering cellular components during this process.

This study found that the once-daily gel combining calcipotriene and betamethasone dipropionate was more effective and faster in treating scalp psoriasis compared to individual treatments, with a similar safety profile.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.

This review explains the mechanical composition and molecular interactions that determine hair's mechanical properties, without providing any new experimental findings.

This study demonstrates that α-parvin is crucial for epidermal morphogenesis and hair follicle development by mediating integrin-dependent adhesion and actin organization in keratinocytes.

This study suggests that foods and drugs containing sulfhydryl groups may induce or worsen pemphigus vulgaris.