5 citations,
November 2021 in “Skin appendage disorders” Hair loss can cause stress and mental health issues, so treatments should address both the physical and psychological aspects, involving a team of dermatologists, psychologists, and hair specialists.
2 citations,
June 2012 in “Journal of Dermatological Science” The gene HDC is important for the development of hair follicles in newborn mice.
15 citations,
June 2020 in “Experimental Dermatology” Hormones and genes affect hair growth and male baldness.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
3 citations,
December 2022 in “Nutrients” Limonin from young citrus fruits may help with hair growth by affecting cell growth and hair cycle pathways.
1 citations,
June 2021 in “Journal of pharmacopuncture” CBD may help restore hair growth-related protein levels in alopecia caused by hormones or other factors.
375 citations,
July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
August 2022 in “Precision Clinical Medicine” JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.
February 2024 in “International journal of molecular sciences” UV exposure reduced hair shine in mice, but minoxidil helped restore it.
56 citations,
January 2021 in “Clinical and Experimental Medicine” The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.
3 citations,
January 2017 in “Yonsei Medical Journal” Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.
13 citations,
March 2020 in “Genes” Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
1 citations,
April 2022 in “BMC Genomics” Researchers found genes linked to hair loss in male giant pandas.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
130 citations,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
May 2024 in “Drug discovery today” Thyroid receptor β can help develop new drugs to treat hair loss.
150 citations,
April 1999 in “Dermatologic Clinics” Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.
56 citations,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
November 2023 in “Frontiers in cell and developmental biology” Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
October 2023 in “Animal production science” Vitamin A deficiency changes cattle hair structure, while pregnancy may improve it, suggesting hair can indicate cattle health.
24 citations,
November 2019 in “Experimental Dermatology” PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
12 citations,
November 2020 in “Journal of Dermatological Science” Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
223 citations,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
March 2009 in “Medical & surgical dermatology” Women with androgenetic alopecia have fewer terminal hairs, phenol in nail surgery is safe, and a new hair transplant method is faster and less damaging.
6 citations,
November 2007 in “British Journal of Dermatology” Fulvestrant solution doesn't help hair loss in men and postmenopausal women.
3 citations,
May 2021 in “Dermatologic Clinics” The document concludes that more research is needed to understand hair loss in men and to find new treatments.
2 citations,
January 2022 in “Stem cell biology and regenerative medicine” Extracellular vesicles, including exosomes from certain cells, can stimulate hair growth.
7 citations,
February 2016 in “Dermatology and therapy” t-Flavanone helps improve male pattern hair loss by making hair roots stronger.
68 citations,
May 2018 in “PLOS Biology” Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
10 citations,
July 2018 in “Our Dermatology Online” Some vitamins and minerals are important for preventing hair loss, but treating hair loss with them without a known deficiency is not proven effective.