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Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Different light affects cell functions and can help treat skin conditions.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.

Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.

Macroalgae compounds offer sustainable, effective benefits for cosmetics.

Exosomes could be effective for improving skin health and treating skin diseases.

Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

JAK inhibitors show promise for treating various skin diseases.

Platelet-derived products help regenerate tissue and are used in various skin and hair treatments.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Melatonin improved secondary hair growth in goats but didn't affect primary hair density or litter size.

Mesenchymal stem cells could help treat aging-related diseases better than current methods.

Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.

Stem cell and platelet-rich plasma therapies show promise for COVID-19 related hair loss, but more research is needed.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Topical calcitriol-analogs can reduce hair loss caused by chemotherapy.

Nanocarrier technology in cosmetics improves ingredient delivery and effectiveness while reducing side effects.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Skin cysts might help advance stem cell treatments to repair skin.

The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.

NK cells play a role in skin diseases like eczema and psoriasis.

A new tool can analyze hair to detect changes due to hormones, genetics, and aging.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.