Melatonin's Effect on Hair Follicles in a Goat (Capra Hircus) Animal Model
April 2024
in “Frontiers in endocrinology (Lausanne)”
TLDR Melatonin improved secondary hair growth in goats but didn't affect primary hair density or litter size.
The study "Melatonin’s effect on hair follicles in a goat (Capra hircus) animal model" conducted a meta-analysis of 22 studies to investigate the impact of melatonin on hair growth and goat litter size. The research found that melatonin did not affect primary follicle density or litter size in goats, but it was positively correlated with secondary follicle growth, cashmere yield, and fiber length. It also positively influenced the development of goat oocytes to blastocysts in vitro. The study suggests that goats could serve as a valuable animal model for human alopecia research and highlights the potential role of melatonin in promoting scalp hair growth, particularly in men with androgenetic alopecia.
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Cited in this study
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research Effects of melatonin administration to cashmere goats on cashmere production and hair follicle characteristics in two consecutive cashmere growth cycles
Melatonin improved cashmere production in goats during the first cycle but had no lasting effects on the next cycle.
research Melatonin supplement induced the hair follicle development in offspring rex rabbits
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research Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis
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