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research Melatonin promotes Cashmere goat (Capra hircus) secondary hair follicle growth: a view from integrated analysis of long non-coding and coding RNAs

32 citations , May 2018 in “Cell Cycle”

This study found that melatonin exposure promoted hair follicle fiber growth in Cashmere goat cultures, potentially influencing pathways related to the microvascular system and extracellular matrix.

research Shh Gene Regulates the Proliferation and Apoptosis of Dermal Papilla Cells to Affect Its Differential Expression in Secondary Hair Follicle Growth Cycle of Cashmere Goats

7 citations , July 2024 in “Animals”

In this study, the researchers observed that higher expression of the Sonic hedgehog gene in cashmere goats' hair follicle cycles is associated with increased cell proliferation and reduced apoptosis, suggesting its role in enhancing cashmere quality.

research Melatonin promotes Cashmere goat (Capra hircus) secondary hair follicle growth: a view from integrated analysis of long non-coding and coding RNAs

January 2021 in “Figshare”

This study reported that exposure to melatonin promoted hair follicle fiber growth in an in vitro Cashmere goat model, potentially by influencing pathways related to the extracellular matrix and microvascular system.

research Melatonin promotes Cashmere goat (Capra hircus) secondary hair follicle growth: A view from integrated analysis of long non-coding and coding RNAs

January 2018 in “Figshare”

This study found that melatonin exposure promoted growth in Cashmere goat hair follicles in vitro and suggested that lncRNAs play a key role in regulating this process, particularly through pathways involving the microvascular system and extracellular matrix.

research Epigenetic and transcriptional profiling of secondary hair follicle stem cells during cashmere growth

March 2026 in “Scientific Data”

This study mapped the genome-wide epigenetic landscape in secondary hair follicle stem cells of goats, revealing distinct histone modification signatures associated with cashmere fiber cycling during different stages of hair growth.

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Community Join

5 / 238 results

community It’s all about the stem cells…

53 upvotes 4 years ago

Hair loss is linked to the loss of stem cells in hair follicles, and potential treatments include gene editing and microneedling. Discussions also mention using Minoxidil, finasteride, and dermarolling to improve hair growth.

community Secondary shedding, 6 months into oral minoxidil/finasteride 3mg chewables

55 upvotes 4 months ago

The user experienced significant hair regrowth and increased density after six months of using oral minoxidil and finasteride chewables, despite going through a secondary shedding phase. The only side effect mentioned was restlessness, and the user feels healthier overall.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community Why does the same hormone grow your beard and destroy your hairline?

44 upvotes 4 months ago

DHT promotes beard growth but causes scalp hair loss due to inflammation and fibrosis. Treatments like finasteride and minoxidil help with hormonal signals and blood flow but don't address underlying inflammation.

community Whats the goal pf Nizoral and Ketoconzole shampoos?

in Ketoconazole 9 upvotes 1 year ago

Ketoconazole shampoos are primarily for dandruff and fungus but may aid hair growth slightly, though results are minor compared to finasteride and minoxidil. Users report it helps with scalp health and inflammation, but it can dry out hair if used too often.

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Learn

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learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Follicusan

learn Hair Transplant

Can hair be taken from other parts of the body for hair transplantation? Body hair can be used for transplantation but is generally a secondary option.
What is a hair transplant? A hair transplant is a surgical procedure that relocates hair follicles to areas of thinning.

learn Follistatin

What is follistatin, and how does it influence hair follicle growth and regeneration? Follistatin blocks activin and related growth-inhibiting proteins, which mouse studies link to hair follicle development and cycling; the only verifiable human evidence is a single small 2011 phase 1 injection trial, so follistatin remains experimental and is not an approved hair-loss treatment.

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