August 2025 in “International Journal of Biological Macromolecules” A new hydrogel can kill resistant bacteria and help heal infected burn wounds.
56 citations
,
December 1978 in “The Journal of Dermatologic Surgery and Oncology” This study reported successful and cosmetically acceptable repigmentation of leukoderma in three patients using minigrafts of normally pigmented, autologous skin.
26 citations
,
August 2016 in “ACS Applied Materials & Interfaces” In this study, cell membrane remodeling with a thermoresponsive boronic acid copolymer was shown to rapidly form spheroids from cancer or cardiac cell lines under standard conditions, promising advances in tissue engineering.
24 citations
,
September 2019 in “Experimental cell research” This study found that BMP2 increased PTEN expression and induced autophagy, promoting hair follicle stem cell differentiation in both in vitro models and a mouse wound model.
5 citations
,
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports on an ongoing Phase I/IIa clinical trial of ex vivo gene therapy for treating severe Recessive Dystrophic Epidermolysis Bullosa, involving six adult participants with COL7A1 mutations resulting in deficient type VII collagen production.
20 citations
,
August 2005 in “The Journal of laboratory and clinical medicine” In this study, researchers observed that epidermal damage may increase susceptibility to Bacillus anthracis infection, allowing it access through hair follicles and the denuded dermis in mice.
7 citations
,
January 2023 in “Biofabrication” This study developed microfluidic-assisted GelMA-MSC/HAD-EPC microspheres that efficiently generated hair follicles in nude mice, suggesting a promising strategy for advancing hair-regenerative medicine.
2 citations
,
December 2021 in “Aesthetic surgery journal” This study found that a silicone gel dressing was well-tolerated and may accelerate early wound healing compared to Bacitracin in patients undergoing follicular unit extraction, but both achieved similar outcomes by day 7.
22 citations
,
February 2023 in “Heliyon” This study reports that a heparin-based sericin hydrogel encapsulating basic fibroblast growth factor significantly accelerated wound healing in mice by enhancing vascularization, re-epithelialization, and collagen deposition.
10 citations
,
August 2023 in “The EMBO Journal” This study explored the epigenetic mechanisms of dermal fibroblast progenitor differentiation and found that the repressive chromatin profile from H3K27me3 prevents these progenitors from reforming skin in allograft assays, despite their multipotent potential.
January 2024 in “Wiadomości Lekarskie” In this study, wounds treated with a combination of 0.02% Decamethoxine and Blastomunil showed enhanced healing and epithelization by the 14th day, leveraging the immunomodulatory and antimicrobial properties of the agents.
13 citations
,
February 2017 in “Science” Turning scar-forming cells into fat cells can reduce scarring.
2 citations
,
November 1998 in “Journal of The European Academy of Dermatology and Venereology” This study focused on the ultrastructural and immunohistochemical aspects of dermal mast cells in systemic mastocytosis and their interaction with the epidermal melanin unit.
28 citations
,
April 2023 in “Stem cell research & therapy” This study reviews the roles and mechanisms of MSC-derived exosomes in wound healing, noting their potential as promising cell-free therapies for cutaneous regeneration.
9 citations
,
May 2022 in “Actas Dermo-Sifiliográficas” This study found that basal cell carcinoma exhibits altered expression patterns of CD10, p63, BCL-2, and EMA proteins compared to normal skin, with notable differences in staining and reactivity.
5 citations
,
January 2004 This paper describes the cellular and molecular processes involved in dermal tissue repair and reports no new experimental results.
16 citations
,
August 2023 in “Tissue Engineering and Regenerative Medicine”
November 2025 in “IECCMEXICO” This review found that adipose-derived stem cells and stromal vascular fraction have robust clinical benefits in aesthetic surgery, particularly in facial rejuvenation, scar treatment, and volumetric restoration, with favorable safety profiles.
2 citations
,
October 2022 in “British journal of haematology” This study reports the first successful use of zanubrutinib to treat a 15-year-old Chinese girl with severe refractory Evans' syndrome, resulting in a sustained recovery of platelet counts and haemoglobin levels.
This study found that a mesenchymal stromal cell-derived regenerative extracellular matrix (rECM) significantly accelerated wound closure and improved healing in diabetic mice, also enhancing nerve and blood vessel formation compared to controls.
9 citations
,
August 2025 in “Current Issues in Molecular Biology” This review discusses the role of extracellular vesicles in bone regeneration and their potential as therapeutics, highlighting challenges like standardization and safety for clinical application, but it reports no new clinical results.
April 2023 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study concluded that mesenchymal stem cells from adipose tissue harvested using laser-assisted liposuction with selective photo-stimulation are as effective and low-risk for cell therapy as those obtained through conventional liposuction, based on their differentiation potential, cellular proliferation, and cytokine expression.
October 2025 in “Frontiers in Immunology” This study explores the potential of platelet-rich plasma (PRP) as a novel adjuvant therapy for eczema, positing that it may alleviate inflammation, enhance skin barrier function, and reduce recurrence.
3 citations
,
January 2021 in “OALib” This review discusses current research and interest in extracellular vesicles for applications in plastic surgery and underscores the need for standardized protocols and further evidence to inform clinical use.
7 citations
,
June 2022 in “Frontiers in Medicine” This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.
This study found that Fraser's Dolphin, a tight-skinned mammal, can regenerate complex skin architecture with minimal scarring after large full-thickness wounds, even in high-tension environments, offering insights into regenerative healing mechanisms typically obscured by fibrotic responses.
24 citations
,
November 2023 in “Nature” In this study, researchers demonstrated that the expression of the oncogene SmoM2 leads to basal cell carcinoma in the ear epidermis of mice but not in the back skin, with differences in susceptibility linked to the composition of the extracellular matrix.
6 citations
,
September 2017 in “Experimental and Therapeutic Medicine” This study found that two short peptides derived from pigment epithelium-derived factor significantly accelerated full-thickness skin wound healing in mice through mechanisms that may involve increased cell proliferation and stem cell mobilization.
This review discusses the potential of extracellular vesicles from various sources for skin rejuvenation and cosmetic use, noting promising results, especially with mesenchymal stem cell-derived vesicles, but reports no new clinical results.
29 citations
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October 2010 in “Acta Biomaterialia”