87 citations
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February 2004 in “Plastic and Reconstructive Surgery” In this study, researchers achieved complete reepithelialization and hair growth on a burn-injured scalp using a tissue-engineered dermal template with early micrograft hair follicle implantation.
169 citations
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January 2020 in “Burns & Trauma” In this study, autologous platelet-rich plasma improved skin wound healing in mice, associated with reduced inflammation and enhanced angiogenesis and re-epithelialization, but the underlying regulatory mechanism requires further investigation.
14 citations
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July 2022 in “Applied Sciences” This review discusses the potential of extracellular vesicles as cell-free tools in tissue engineering and regenerative medicine, noting their emerging role in promoting tissue repair without the risk of host rejection.
11 citations
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March 2023 in “Stem Cell Research & Therapy” In this study, epidermal stem cells were found to enhance blood vessel formation and support successful one-step transplantation of tissue-engineered skin in a rat model.
October 2025 in “Journal of Nanobiotechnology” This study reports that using a hydrogel-based therapy that dynamically regulates reactive oxygen species helps achieve skin regeneration in infected wounds, promoting organized dermal architecture with improved hair follicle and blood vessel formation, rather than scar formation.
1 citations
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March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that Dermal Fibroblast Progenitors have repressed chromatin profiles which hinder their ability to reform skin in allograft assays despite their differentiation potential.
2 citations
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August 2017 in “Experimental Dermatology” This study developed a new melanocyte cultivation medium without chemical mitogens, melanogenesis enhancers, or bovine products, demonstrating successful proliferation and melanotic differentiation of human melanocytes from hair follicles.
132 citations
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April 2021 in “Stem Cell Research & Therapy” This study found that exosome-incorporated human amniotic membrane scaffolds notably enhanced diabetic skin wound healing in mice, suggesting potential applications for ADSC-derived exosomes in clinical settings.
January 2024 in “Wiadomości Lekarskie” This paper reviews current cell therapies in medicine, highlighting hematopoietic stem cell transplants as a foundational success and the growing application of genetically modified cells like CAR-T and mesenchymal stem cells for various diseases, including blood disorders and autoimmune conditions.
July 2024 in “Journal of Investigative Dermatology” Bioactive peptides improve graft survival and new hair growth.
June 2026 in “International Science Journal” This study reviewed recent advances in regenerative technologies for aesthetic and reconstructive medicine and found that adipose-derived stem cells and platelet-rich plasma are well-established for tissue repair due to their safety and effectiveness, while emerging technologies like exosome-based therapies hold future potential.
36 citations
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December 2004 in “British Journal of Dermatology” This case study reports a peculiar variant of an epidermal cyst in a patient, featuring unique characteristics like brownish, lumpy contents resembling bone marrow.
September 2026 in “Biomedicine & Pharmacotherapy” This study found that a newly developed ultrasound-responsive hydrogel, incorporating ADSC-derived exosome nanobubbles, substantially improved wound healing in rats by enhancing skin closure, re-epithelialization, and hair follicle regeneration, while potentially reducing scar formation.
3 citations
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November 2005 in “British Journal of Dermatology” In this case study, a 21-year-old man with alopecia universalis experienced temporary hair regrowth after treatment with recombinant human bone morphogenetic protein-2 following a tibial fracture.
26 citations
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September 2018 in “Colloids and Surfaces B: Biointerfaces” This study reported that a novel liposomal formulation, SP-bFGF-SF-LIP, enhanced bFGF stability and skin permeability, significantly improving hair follicle recovery and wound healing in a mouse model.
November 2024 in “Journal of Investigative Dermatology”
April 2017 in “Journal of Dermatological Science” This study found that B cells have dual roles in tumor immunity, with regulatory B cells potentially hindering immune responses against tumors in the melanoma mouse model.
This study found that prophylactically administering amotosalen-treated allogeneic donor T cells at transplantation significantly improved immune reconstitution and protection against murine cytomegalovirus infection without inducing graft-versus-host disease.
13 citations
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December 2021 in “Journal of Cellular and Molecular Medicine” This case report observed that treatment with human placental mesenchymal stromal cell-derived exosome-enriched extracellular vesicles may improve symptoms of chronic cutaneous graft-versus-host disease, including hyperpigmentation and skin ulcers, in a patient resistant to conventional therapies.
August 2019 in “Journal of Invertebrate Pathology” This study observed that different alkaline buffers had a significant impact on the volume of liquid consumed by fall armyworm larvae, emphasizing the importance of measuring imbibed volumes to reduce dose errors in bioassays.
2 citations
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March 2023 in “Annals of Translational Medicine” This study analyzed trends in tissue expansion research and identified acellular dermal matrix's effect on breast reconstruction complications as a current key topic, with patient-activated controlled expansion as a potential future focus.
July 2025 in “Current Stem Cell Research & Therapy” This analysis found that mesenchymal stem cell-derived exosomes show potential as a safe and effective treatment for various skin and subcutaneous tissue diseases.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.
This source reviews current understanding of fibroblast lineage differentiation and its role in wound healing, highlighting the potential to reprogram adult cells for scar-free repair by emulating fetal-like regenerative states.
1 citations
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February 2024 in “Journal of Microscopy and Ultrastructure” In this study, intravenous injection of exosomes derived from mesenchymal stromal cells accelerated wound healing and improved skin tissue regeneration in adult male rats.
July 2022 in “European Journal of Dermatology” In this study, researchers found that patients with psoriasis had a higher probability of achieving and maintaining a clinical response using brodalumab compared to ustekinumab over 52 weeks, as measured by a multistate modelling approach based on absolute PASI scores.
3 citations
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January 2014 Collagen XVIII and Bmx tyrosine kinase are important for hair growth and skin cancer development.
June 2025 in “Stem Cells and Cloning Advances and Applications” In this study, researchers demonstrated that their technology efficiently produces CFx-δ2 from stem cells and accelerates wound healing by enhancing fibroblast activity, reducing inflammation, and promoting blood vessel formation.
92 citations
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March 2016 in “Developmental Cell” Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
2 citations
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March 2005 in “Cancer biology & therapy” This study found that 95% of untreated advanced-stage follicular lymphoma patients responded to a single course of the Bexxar regimen, with 75% achieving complete remission and remaining disease-free for years.