Epidermal Cyst Containing Numerous Spherules of Keratin

    December 2004 in “ British Journal of Dermatology
    Hideo Hattori
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    Studysummary This case study reports a peculiar variant of an epidermal cyst in a patient, featuring unique characteristics like brownish, lumpy contents resembling bone marrow.
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    The document described a peculiar variant of an epidermal cyst found in a 56-year-old man, which differed from a typical epidermal cyst. While one of the man's subcutaneous nodules was an ordinary epidermal cyst, the other exhibited unique characteristics. It was soft, with a brownish, lumpy content resembling bone marrow. Microscopically, the cyst was lined with epidermis containing granular cells and orthokeratinization, and its contents included numerous keratin spherules. These spherules formed just above the keratinous layer of the lining epithelium, and there were shadow cell-like foci with mild mineralization observed.
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