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Scalp hair follicle cells help protect and heal skin in certain skin conditions.

This study found that combining AMD-3100 with FK506 in subimmunosuppressive doses enhanced stem cell release from bone marrow, resulting in 25% faster epithelialization in excisional wounds in rats and mice.

In this study, researchers developed a novel method using ultrasound stimulation and a hydrogel delivery system to enhance the regenerative effects of stem cell-derived extracellular vesicles on severe skin injuries, resulting in improved healing and hair follicle regeneration in a mouse model.

The study found that adipose-derived mesenchymal stem cells obtained via laser-assisted liposuction with selective photo-stimulation are comparable in differentiation potential and tumorigenic risk to those from conventional liposuction for cell therapy applications.

This study found that mesenchymal progenitor cells from human hair roots seeded onto polymer scaffolds stimulated the production of mineralized proteins, enhancing bone-like structures, with optimal results at a pore size of 35 µm.

This study found that hair follicle stem cells show good biocompatibility with a heterogeneous bladder acellular matrix in vitro and in vivo, supporting potential use in bladder repair.

In this review, the authors explored the diverse roles of fibroblasts in wound healing, suggesting that understanding their complexity could lead to better insights into wound pathologies and the development of new treatments.

This review found that vesicle-based therapies, including mammalian MSC-derived and plant-derived vesicles, consistently promote wound healing in preclinical models of thermal injury and may offer a safer alternative to live cell transplants.

This study developed a new multifunctional medical dressing using Bletilla striata polysaccharide and ethanol extract that demonstrated hemostatic, antibacterial, and significant wound healing effects, as evidenced by quicker healing rates and improved skin conditions in treated wounds compared to controls.

This study concludes that fetal skin cells can significantly enhance wound healing and reduce scarring when used to treat severe burns and various wounds in children.

Stem cell therapies show promise for healing skin wounds but need more testing.

This study reviews the role of exosomes in regenerative aesthetics, highlighting their potential in treating conditions like photoaging and wound healing through mechanisms like matrix remodeling and immunomodulation, while also noting advancements in exosome isolation techniques and regulatory considerations.

This study found that transplanting hair follicle bulge-derived stem cells in rats enhanced skin regeneration during expansion by differentiating into several skin-related cells and increasing the expression of growth factors.

This research found that a biodegradable fibrous membrane incorporating fibroblast-derived ECM accelerated wound healing and improved neovascularization in a mouse model.

This review discusses cutaneous extramedullary haematopoiesis and its potential mechanisms but reports no new clinical findings.

In a study of 147 patients with androgenic alopecia, those who received hair transplantation combined with platelet-rich plasma injections experienced better hair regrowth and smaller areas of hair loss compared to those who only had hair transplantation.

This review discusses how research on keratin biology has enhanced the understanding of epidermolysis bullosa simplex and indicates potential new therapeutic approaches, but it presents no new experimental results.

This review discusses the role of extracellular vesicles from specific skin cells in wound healing, emphasizing their potential in regenerative medicine and reporting no new experimental results.

This study found that glioblastoma cancer stem cells avoid immune suppression by downregulating TLR4, and restoring TLR4 signaling may reduce tumor growth and self-renewal.

This study observed that exosomes derived from adipose-derived stem cells significantly enhanced bone marrow mesenchymal stem cell migration and osteogenesis, leading to improved bone regeneration in a rat model of calvarial defects.

This study reported that the use of composite RGDmix hydrogel improved the survival and proliferation of human amniotic mesenchymal stem cells and increased growth factor expression, enhancing wound healing through the RGDSP/integrin αv/PI3K/AKT signaling pathway.

This study found that CRABP1, Nestin, and Ephrin B2 are expressed in both the tumor stroma and invasive front of skin adnexal tumors and basal cell carcinomas.

This study concluded that leucocyte-rich PRP has a continuous stimulatory effect on human fibroblast cells, enhancing their proliferation, migration, and impacting gene expression of the extracellular matrix and adhesion molecules.

This case study suggests a possible rare follicular variant of neutrophilic dermatosis linked to myelogenous leukemia, where skin lesions improved following chemotherapy treatment.

In this review, the researchers highlight the role of fibroblasts in regulating the extracellular matrix and immune responses, emphasizing the impact on macrophages and potential therapeutic insights for fibrotic diseases and cancer.

This review discusses the advances and challenges of using mesenchymal stem cell-derived extracellular vesicles in therapeutic applications and reports no new clinical findings.

This narrative review highlights the potential of exosomes as a promising platform for precision diagnostics, regenerative medicine, and targeted therapeutics in dermatology, while noting challenges such as standardization, manufacturing, and regulatory approval that must be resolved before widespread clinical use.

In this study, researchers demonstrated that fibroblasts derived from human embryonic stem cells can be used to create tissue-engineered dermal substitutes, effectively repairing mouse skin wounds within 20 days, highlighting a promising method for clinical applications in skin repair.

This study found that loss of integrin-β4 or its ligand, laminin-α3β3ɣ2, in keratinocytes increases differentiation via delamination, and demonstrated a role for hemidesmosomes in epidermal differentiation through both mitotic and non-mitotic mechanisms, influenced by Notch signaling.

This study developed a biodegradable nanofibrous biofilm that attracts skin-related cells and accelerates blood vessel formation, potentially improving skin wound healing.